@article{115c86b3e1d243cd8eeb164faf9cb8d1,
title = "Cross-coupling of [11C]methyllithium for 11C-labelled PET tracer synthesis",
abstract = "The cross-coupling of aryl bromides with [11C]CH3Li for the labelling of a variety of tracers for positron emission tomography (PET) is presented. The radiolabelled products were obtained in excellent yields, at rt and after short reaction times (3-5 min) compatible with the half-life of 11C (20.4 min). The automation of the protocol on a synthesis module is investigated, representing an important step towards a fast method for the synthesis of 11C-labelled compounds for PET imaging.",
author = "Hugo Helbert and Antunes, \{Ines Farinha\} and Gert Luurtsema and Wiktor Szymanski and Feringa, \{Ben L\} and Elsinga, \{Philip H\}",
note = "Funding Information: B. L. F. acknowledges financial support from The Netherlands Organization for Scientific Research, the Royal Netherlands Academy of Arts and Sciences (KNAW), and the Ministry of Education, Culture and Science (Gravitation program 024.60 1035). Bram Maas is kindly acknowledged for operating the cyclotron and providing the [11C]CH4. Publisher Copyright: {\textcopyright} The Royal Society of Chemistry.",
year = "2021",
month = jan,
day = "7",
doi = "10.1039/d0cc05392a",
language = "English",
volume = "57",
pages = "203--206",
journal = "Chemical communications (Cambridge, England)",
issn = "1359-7345",
publisher = "ROYAL SOC CHEMISTRY",
number = "2",
}