Current and Future Use of Long Axial Field-of-View Positron Emission Tomography/Computed Tomography Scanners in Clinical Oncology

Mostafa Roya; Samaneh Mostafapour; Philipp Mohr; Laura Providência; Zekai Li; Johannes H van Snick; Adrienne H Brouwers; Walter Noordzij; Antoon T M Willemsen; Rudi A J O Dierckx; Adriaan A Lammertsma; Andor W J M Glaudemans; Charalampos Tsoumpas; Riemer H J A Slart; Joyce van Sluis

doi:10.3390/cancers15215173

Current and Future Use of Long Axial Field-of-View Positron Emission Tomography/Computed Tomography Scanners in Clinical Oncology

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Abstract

The latest technical development in the field of positron emission tomography/computed tomography (PET/CT) imaging has been the extension of the PET axial field-of-view. As a result of the increased number of detectors, the long axial field-of-view (LAFOV) PET systems are not only characterized by a larger anatomical coverage but also by a substantially improved sensitivity, compared with conventional short axial field-of-view PET systems. In clinical practice, this innovation has led to the following optimization: (1) improved overall image quality, (2) decreased duration of PET examinations, (3) decreased amount of radioactivity administered to the patient, or (4) a combination of any of the above. In this review, novel applications of LAFOV PET in oncology are highlighted and future directions are discussed.

Original language	English
Article number	5173
Number of pages	21
Journal	Cancers
Volume	15
Issue number	21
DOIs	https://doi.org/10.3390/cancers15215173
Publication status	Published - 27-Oct-2023

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Roya, M., Mostafapour, S., Mohr, P., Providência, L., Li, Z., van Snick, J. H., Brouwers, A. H., Noordzij, W., Willemsen, A. T. M., Dierckx, R. A. J. O., Lammertsma, A. A., Glaudemans, A. W. J. M., Tsoumpas, C., Slart, R. H. J. A., & van Sluis, J. (2023). Current and Future Use of Long Axial Field-of-View Positron Emission Tomography/Computed Tomography Scanners in Clinical Oncology. Cancers, 15(21), Article 5173. https://doi.org/10.3390/cancers15215173

@article{1b2f25d0843041a788ae8d1c8166431f,

title = "Current and Future Use of Long Axial Field-of-View Positron Emission Tomography/Computed Tomography Scanners in Clinical Oncology",

abstract = "The latest technical development in the field of positron emission tomography/computed tomography (PET/CT) imaging has been the extension of the PET axial field-of-view. As a result of the increased number of detectors, the long axial field-of-view (LAFOV) PET systems are not only characterized by a larger anatomical coverage but also by a substantially improved sensitivity, compared with conventional short axial field-of-view PET systems. In clinical practice, this innovation has led to the following optimization: (1) improved overall image quality, (2) decreased duration of PET examinations, (3) decreased amount of radioactivity administered to the patient, or (4) a combination of any of the above. In this review, novel applications of LAFOV PET in oncology are highlighted and future directions are discussed.",

author = "Mostafa Roya and Samaneh Mostafapour and Philipp Mohr and Laura Provid{\^e}ncia and Zekai Li and \{van Snick\}, \{Johannes H\} and Brouwers, \{Adrienne H\} and Walter Noordzij and Willemsen, \{Antoon T M\} and Dierckx, \{Rudi A J O\} and Lammertsma, \{Adriaan A\} and Glaudemans, \{Andor W J M\} and Charalampos Tsoumpas and Slart, \{Riemer H J A\} and \{van Sluis\}, Joyce",

year = "2023",

month = oct,

day = "27",

doi = "10.3390/cancers15215173",

language = "English",

volume = "15",

journal = "Cancers",

issn = "2072-6694",

publisher = "MDPI AG",

number = "21",

}

Roya, M , Mostafapour, S , Mohr, P , Providência, L , Li, Z, van Snick, JH, Brouwers, AH , Noordzij, W , Willemsen, ATM , Dierckx, RAJO, Lammertsma, AA, Glaudemans, AWJM , Tsoumpas, C , Slart, RHJA & van Sluis, J 2023, 'Current and Future Use of Long Axial Field-of-View Positron Emission Tomography/Computed Tomography Scanners in Clinical Oncology', Cancers, vol. 15, no. 21, 5173. https://doi.org/10.3390/cancers15215173

TY - JOUR

T1 - Current and Future Use of Long Axial Field-of-View Positron Emission Tomography/Computed Tomography Scanners in Clinical Oncology

AU - Roya, Mostafa

AU - Mostafapour, Samaneh

AU - Mohr, Philipp

AU - Providência, Laura

AU - Li, Zekai

AU - van Snick, Johannes H

AU - Brouwers, Adrienne H

AU - Noordzij, Walter

AU - Willemsen, Antoon T M

AU - Dierckx, Rudi A J O

AU - Lammertsma, Adriaan A

AU - Glaudemans, Andor W J M

AU - Tsoumpas, Charalampos

AU - Slart, Riemer H J A

AU - van Sluis, Joyce

PY - 2023/10/27

Y1 - 2023/10/27

N2 - The latest technical development in the field of positron emission tomography/computed tomography (PET/CT) imaging has been the extension of the PET axial field-of-view. As a result of the increased number of detectors, the long axial field-of-view (LAFOV) PET systems are not only characterized by a larger anatomical coverage but also by a substantially improved sensitivity, compared with conventional short axial field-of-view PET systems. In clinical practice, this innovation has led to the following optimization: (1) improved overall image quality, (2) decreased duration of PET examinations, (3) decreased amount of radioactivity administered to the patient, or (4) a combination of any of the above. In this review, novel applications of LAFOV PET in oncology are highlighted and future directions are discussed.

AB - The latest technical development in the field of positron emission tomography/computed tomography (PET/CT) imaging has been the extension of the PET axial field-of-view. As a result of the increased number of detectors, the long axial field-of-view (LAFOV) PET systems are not only characterized by a larger anatomical coverage but also by a substantially improved sensitivity, compared with conventional short axial field-of-view PET systems. In clinical practice, this innovation has led to the following optimization: (1) improved overall image quality, (2) decreased duration of PET examinations, (3) decreased amount of radioactivity administered to the patient, or (4) a combination of any of the above. In this review, novel applications of LAFOV PET in oncology are highlighted and future directions are discussed.

U2 - 10.3390/cancers15215173

DO - 10.3390/cancers15215173

M3 - Review article

C2 - 37958347

SN - 2072-6694

VL - 15

JO - Cancers

JF - Cancers

IS - 21

M1 - 5173

ER -

Current and Future Use of Long Axial Field-of-View Positron Emission Tomography/Computed Tomography Scanners in Clinical Oncology

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