Current Concepts and Future Perspectives on Intraoperative Fluorescence Imaging in Cancer: Clinical Need

Gooitzen M. van Dam, Vasilis Ntziachristos*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)

Abstract

Progress with technology and regulatory approvals has recently allowed the successful clinical translation of fluorescence molecular imaging to intra-operative applications. Initial studies have demonstrated a promising outlook for imaging cancer micro-foci, margins and lymph-nodes. However, not all surgeries will benefit equally from fluorescence guidance. This review paper outlines the clinical necessity for improving surgical procedures in the most prevalent solid tumors worldwide, demarcates major challenges currently encountered intra-operatively and outlines the role of imaging fluorescent agents during the operation.

Original languageEnglish
Pages (from-to)233-243
Number of pages11
JournalCurrent medical imaging reviews
Volume8
Issue number3
Publication statusPublished - Aug-2012

Keywords

  • Cancer
  • Intraoperative Imaging
  • Near-infrared Fluorescence
  • Tumor
  • Resection Margin
  • Lymph Node Detection
  • CIRCUMFERENTIAL MARGIN INVOLVEMENT
  • CELL LUNG-CANCER
  • POSITRON-EMISSION-TOMOGRAPHY
  • EPITHELIAL OVARIAN-CARCINOMA
  • CONE-BEAM CT
  • CONTRAST-ENHANCED ULTRASONOGRAPHY
  • COLORECTAL LIVER METASTASES
  • TOTAL MESORECTAL EXCISION
  • RECURRENT RECTAL-CANCER
  • BYPASS GRAFT PATENCY

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