Abstract
Cycloruthenated complexes obtained by direct C–H activation of enantiopure aromatic primary and secondary amines are efficient catalysts in asymmetric hydride transfer reaction. Reduction of acetophenone has been achieved rapidly with enantiomeric excesses (ee’s) ranging from 38 to 89 %. The importance of Ru–C bond in the catalytic efficiency is highlighted.
| Original language | English |
|---|---|
| Pages (from-to) | 457-462 |
| Number of pages | 6 |
| Journal | Pure and Applied Chemistry |
| Volume | 78 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2006 |
Keywords
- ruthenium
- amines
- catalysis
- reduction
- high-throughput experiments
- ketones
- enantioselectivity
- chirality
- cyclometallation