Cytogenetic support for early malignant change in a diffuse neurofibroma not associated with neurofibromatosis

WM Molenaar, T Dijkhuizen, J vanEchten, HJ Hoekstra, E vandenBerg

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    12 Citations (Scopus)

    Abstract

    A 62-year-old woman presented with a solitary diffuse neurofibroma; a second recurrence showed features indicative of malignancy, but insufficient for a certain histologic diagnosis. Cytogenetic analysis revealed abnormalities previously described in malignant peripheral nerve sheath tumors and not in their benign counterparts, thus supporting the histologic suspicion of emerging malignancy. (C) 1997 Elsevier Science Inc., 1997.

    Original languageEnglish
    Pages (from-to)70-72
    Number of pages3
    JournalCancer Genetics and Cytogenetics
    Volume97
    Issue number1
    Publication statusPublished - Aug-1997

    Keywords

    • TUMORS
    • CHROMOSOME-22
    • ABERRATIONS
    • TYPE-1

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