Cytokine Design

Vicente R Tur (Inventor), Albert M. van der Sloot (Inventor), Margaret M. Mullally (Inventor), Robbert H Cool (Inventor), Eva E Szegezdi (Inventor), Afshin Samali (Inventor), Gregorio Fernandez-Ballester (Inventor), Luis Serrano (Inventor), Wim Quax (Inventor)

Research output: Patent


The present invention relates to novel methods for the design of proteins, in particular, cytokines. These methods allow the stabilisation of such cytokines, as well as modification of their selectivity/specificity for their cognate receptors. The invention also relates to various modified proteins that have been designed by the methods of the invention.

Original languageEnglish
Patent numberUS2008044376
IPCG06F 19/ 22 A N
Priority date06/12/2004
Publication statusPublished - 21-Feb-2008

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