Cytokine Design

Vicente R Tur; Albert M.  van der Sloot; Margaret M. Mullally; Robbert H Cool; Eva E Szegezdi; Afshin Samali; Gregorio Fernandez-Ballester; Luis Serrano; Wim Quax

Cytokine Design

Vicente R Tur (Inventor), Albert M. van der Sloot (Inventor), Margaret M. Mullally (Inventor), Robbert H Cool (Inventor), Eva E Szegezdi (Inventor), Afshin Samali (Inventor), Gregorio Fernandez-Ballester (Inventor), Luis Serrano (Inventor), Wim Quax (Inventor)

Research output: Patent

Abstract

The present invention relates to novel methods for the design of proteins, in particular, cytokines. These methods allow the stabilisation of such cytokines, as well as modification of their selectivity/specificity for their cognate receptors. The invention also relates to various modified proteins that have been designed by the methods of the invention.

Original language	English
Patent number	US2008044376
IPC	G06F 19/ 22 A N
Priority date	06/12/2004
Publication status	Published - 21-Feb-2008

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title = "Cytokine Design",

abstract = "The present invention relates to novel methods for the design of proteins, in particular, cytokines. These methods allow the stabilisation of such cytokines, as well as modification of their selectivity/specificity for their cognate receptors. The invention also relates to various modified proteins that have been designed by the methods of the invention.",

author = "Tur, {Vicente R} and {van der Sloot}, {Albert M.} and Mullally, {Margaret M.} and Cool, {Robbert H} and Szegezdi, {Eva E} and Afshin Samali and Gregorio Fernandez-Ballester and Luis Serrano and Wim Quax",

year = "2008",

month = feb,

day = "21",

language = "English",

type = "Patent",

note = "US2008044376; G06F 19/ 22 A N",

}

TY - PAT

T1 - Cytokine Design

AU - Tur, Vicente R

AU - van der Sloot , Albert M.

AU - Mullally, Margaret M.

AU - Cool, Robbert H

AU - Szegezdi, Eva E

AU - Samali, Afshin

AU - Fernandez-Ballester, Gregorio

AU - Serrano, Luis

AU - Quax, Wim

PY - 2008/2/21

Y1 - 2008/2/21

N2 - The present invention relates to novel methods for the design of proteins, in particular, cytokines. These methods allow the stabilisation of such cytokines, as well as modification of their selectivity/specificity for their cognate receptors. The invention also relates to various modified proteins that have been designed by the methods of the invention.

AB - The present invention relates to novel methods for the design of proteins, in particular, cytokines. These methods allow the stabilisation of such cytokines, as well as modification of their selectivity/specificity for their cognate receptors. The invention also relates to various modified proteins that have been designed by the methods of the invention.

M3 - Patent

M1 - US2008044376

ER -