Abstract
The present invention relates to novel methods for the design of proteins, in particular, cytokines. These methods allow the stabilisation of such cytokines, as well as modification of their selectivity/specificity for their cognate receptors. The invention also relates to various modified proteins that have been designed by the methods of the invention.
Original language | English |
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Patent number | US2008044376 |
IPC | G06F 19/ 22 A N |
Priority date | 06/12/2004 |
Publication status | Published - 21-Feb-2008 |