De zuigeling met een vitamine-K-deficiëntiebloeding ondanks adequate profylaxe

Translated title of the contribution: Vitamin K deficiency bleeding in an infant despite adequate prophylaxis

P M van Hasselt, R H J Houwen, A T H van Dijk, T J de Koning

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Vitamin K deficiency in infants can cause life-threatening haemorrhages. To prevent this, neonates in the Netherlands receive an oral dose of 1 mg vitamin K directly after birth. In addition, because breast milk contains little vitamin K, breast-fed infants receive a daily dose of 25 micrograms the first three months. Of three female infants aged 4 weeks, 5 months and 3 months, respectively, two developed an intracranial haemorrhage, which caused death in one. In two cases there were signs of a bleeding tendency, but no tests were done because the patients appeared healthy otherwise. The underlying resorptive disorders, cholestasis and fat malabsorption, caused few symptoms and were discovered only after a vitamin K deficiency bleeding had occurred. In an infant with a bleeding tendency, one should consider the possibility of vitamin K deficiency, even if adequate prophylaxis has been given.

Translated title of the contributionVitamin K deficiency bleeding in an infant despite adequate prophylaxis
Original languageDutch
Pages (from-to)737-40
Number of pages4
JournalNederlands Tijdschrift voor Geneeskunde
Issue number16
Publication statusPublished - 19-Apr-2003
Externally publishedYes


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