Defecatory urge increases cognitive control and intertemporal patience in healthy volunteers

Dongxing Dongxing Zhao, Maura Corsetti, Mehrad Moeini Jazani, Nathalie Weltens, Mirjam Tuk, Tack Jan, Luk Warlop, Lukas Van Oudenhove

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Abstract

Background: Past research has demonstrated that moderate urge to urinate improves inhibitory control, specifically among participants with higher behavioral inhibition sensitivity (BIS). The effect was absent when the urge exceeded intolerable level. The present research examines whether rectal distension‐induced urge to defecate has similar effects.

Methods: The moderate and high defecatory urge were induced by rectal distension in healthy volunteers (n = 35), while they completed Stroop task and monetary delay discounting task. The difference of average reaction time between incongruent and congruent trials in the Stroop task (Stroop interference) and the preference for larger‐later rewards in the delay discounting task were the primary outcomes.

Key Results: Participants with high BIS (n = 17) showed greater ability to inhibit their automatic response tendencies, as indexed by their Stroop interference, under moderate urge relative to no urge (128 ± 41 ms vs 202 ± 37 ms, t64 = 2.07; P = 0.021, Cohen's d: 0.44), but not relative to high urge (154 ± 45 ms, t64 = 1.20; P = 0.12, Cohen's d: 0.30). High BIS participants also showed a higher preference for larger‐later reward in the delay discounting task under high (odds ratio = 1.51 [1.02‐2.25], P = 0.039) relative to no urge, but not relative to moderate urge (odds ratio = 1.02 [0.73‐1.42], P = 0.91). In contrast, rectal distension did not influence performance on either of the tasks in participants with low BIS (n = 18).
Original languageEnglish
Article numbere13600
Number of pages10
JournalNeurogastroenterology and motility
Volume31
Issue number7
Early online date16-Apr-2019
DOIs
Publication statusPublished - Jul-2019

Keywords

  • ANTERIOR CINGULATE CORTEX
  • IRRITABLE-BOWEL-SYNDROME
  • BEHAVIORAL-INHIBITION
  • PAIN
  • ACTIVATION
  • ATTENTION
  • RESPONSES
  • BLADDER
  • SYSTEMS
  • TASK

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