Degradation of halogenated aliphatic compounds: The role of adaptation

Frens Pries; Jan Ploeg , van der; J Dolfing; D.B. Janssen

doi:10.1111/j.1574-6976.1994.tb00140.x

Degradation of halogenated aliphatic compounds: The role of adaptation

Frens Pries
, Jan Ploeg , van der
, J Dolfing
, D.B. Janssen

Research output: Contribution to journal › Article › Academic › peer-review

27 Citations (Scopus)

Abstract

A limited number of halogenated aliphatic compounds can serve as a growth substrate for aerobic microorganisms. Such cultures have (specifically) developed a variety of enzyme systems to degrade these compounds. Dehalogenations are of critical importance. Various heavily chlorinated compounds are not easily biodegraded, although there are no obvious biochemical or thermodynamic reasons why microorganisms should not be able to grow with any halogenated compound. The very diversity of catabolic enzymes present in cultures that degrade halogenated aliphatics and the occurrence of molecular mechanisms for genetic adaptation serve as good starting points for the evolution of catabolic pathways for compounds that are currently still resistant to biodegradation.

Original language	English
Pages (from-to)	279-295
Number of pages	17
Journal	FEMS Microbiology Reviews
Volume	15
Issue number	2-3
DOIs	https://doi.org/10.1111/j.1574-6976.1994.tb00140.x
Publication status	Published - Oct-1994
Event	Symposium on Microbes in Engineered Ecosystems - , Netherlands Duration: 18-Apr-1993 → 21-Apr-1993

Keywords

ADAPTATION
EVOLUTION
DEHALOGENASE
CHLOROACETATE
1,2-DICHLOROETHANE
TRICHLOROETHYLENE
METHYLOSINUS-TRICHOSPORIUM OB3B
XANTHOBACTER-AUTOTROPHICUS GJ10
PSEUDOMONAS-PUTIDA PP3
SOLUBLE METHANE MONOOXYGENASE
GLUTATHIONE-S-TRANSFERASE
BACTERIUM NITROSOMONAS-EUROPAEA
RECOMBINANT ESCHERICHIA-COLI
SP STRAIN N-1074
DICHLOROMETHANE DEHALOGENASE
HALOALKANE DEHALOGENASE

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title = "Degradation of halogenated aliphatic compounds: The role of adaptation",

abstract = "A limited number of halogenated aliphatic compounds can serve as a growth substrate for aerobic microorganisms. Such cultures have (specifically) developed a variety of enzyme systems to degrade these compounds. Dehalogenations are of critical importance. Various heavily chlorinated compounds are not easily biodegraded, although there are no obvious biochemical or thermodynamic reasons why microorganisms should not be able to grow with any halogenated compound. The very diversity of catabolic enzymes present in cultures that degrade halogenated aliphatics and the occurrence of molecular mechanisms for genetic adaptation serve as good starting points for the evolution of catabolic pathways for compounds that are currently still resistant to biodegradation.",

keywords = "ADAPTATION, EVOLUTION, DEHALOGENASE, CHLOROACETATE, 1,2-DICHLOROETHANE, TRICHLOROETHYLENE, METHYLOSINUS-TRICHOSPORIUM OB3B, XANTHOBACTER-AUTOTROPHICUS GJ10, PSEUDOMONAS-PUTIDA PP3, SOLUBLE METHANE MONOOXYGENASE, GLUTATHIONE-S-TRANSFERASE, BACTERIUM NITROSOMONAS-EUROPAEA, RECOMBINANT ESCHERICHIA-COLI, SP STRAIN N-1074, DICHLOROMETHANE DEHALOGENASE, HALOALKANE DEHALOGENASE",

author = "Frens Pries and \{Ploeg , van der\}, Jan and J Dolfing and D.B. Janssen",

note = "Relation: http://www.rug.nl/gbb/ date\_submitted:2009 Rights: University of Groningen, Groningen Biomolecular Sciences and Biotechnology Institute; Symposium on Microbes in Engineered Ecosystems ; Conference date: 18-04-1993 Through 21-04-1993",

year = "1994",

month = oct,

doi = "10.1111/j.1574-6976.1994.tb00140.x",

language = "English",

volume = "15",

pages = "279--295",

journal = "FEMS Microbiology Reviews",

issn = "0168-6445",

publisher = "Oxford University Press",

number = "2-3",

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T1 - Degradation of halogenated aliphatic compounds

T2 - Symposium on Microbes in Engineered Ecosystems

AU - Pries, Frens

AU - Ploeg , van der, Jan

AU - Dolfing, J

AU - Janssen, D.B.

N1 - Relation: http://www.rug.nl/gbb/ date_submitted:2009 Rights: University of Groningen, Groningen Biomolecular Sciences and Biotechnology Institute

PY - 1994/10

Y1 - 1994/10

N2 - A limited number of halogenated aliphatic compounds can serve as a growth substrate for aerobic microorganisms. Such cultures have (specifically) developed a variety of enzyme systems to degrade these compounds. Dehalogenations are of critical importance. Various heavily chlorinated compounds are not easily biodegraded, although there are no obvious biochemical or thermodynamic reasons why microorganisms should not be able to grow with any halogenated compound. The very diversity of catabolic enzymes present in cultures that degrade halogenated aliphatics and the occurrence of molecular mechanisms for genetic adaptation serve as good starting points for the evolution of catabolic pathways for compounds that are currently still resistant to biodegradation.

AB - A limited number of halogenated aliphatic compounds can serve as a growth substrate for aerobic microorganisms. Such cultures have (specifically) developed a variety of enzyme systems to degrade these compounds. Dehalogenations are of critical importance. Various heavily chlorinated compounds are not easily biodegraded, although there are no obvious biochemical or thermodynamic reasons why microorganisms should not be able to grow with any halogenated compound. The very diversity of catabolic enzymes present in cultures that degrade halogenated aliphatics and the occurrence of molecular mechanisms for genetic adaptation serve as good starting points for the evolution of catabolic pathways for compounds that are currently still resistant to biodegradation.

KW - ADAPTATION

KW - EVOLUTION

KW - DEHALOGENASE

KW - CHLOROACETATE

KW - 1,2-DICHLOROETHANE

KW - TRICHLOROETHYLENE

KW - METHYLOSINUS-TRICHOSPORIUM OB3B

KW - XANTHOBACTER-AUTOTROPHICUS GJ10

KW - PSEUDOMONAS-PUTIDA PP3

KW - SOLUBLE METHANE MONOOXYGENASE

KW - GLUTATHIONE-S-TRANSFERASE

KW - BACTERIUM NITROSOMONAS-EUROPAEA

KW - RECOMBINANT ESCHERICHIA-COLI

KW - SP STRAIN N-1074

KW - DICHLOROMETHANE DEHALOGENASE

KW - HALOALKANE DEHALOGENASE

U2 - 10.1111/j.1574-6976.1994.tb00140.x

DO - 10.1111/j.1574-6976.1994.tb00140.x

M3 - Article

SN - 0168-6445

VL - 15

SP - 279

EP - 295

JO - FEMS Microbiology Reviews

JF - FEMS Microbiology Reviews

IS - 2-3

Y2 - 18 April 1993 through 21 April 1993

ER -

Degradation of halogenated aliphatic compounds: The role of adaptation

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Keywords

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