Delineation of organs at risk involved in swallowing for radiotherapy treatment planning

Miranda E. M. C. Christianen, Johannes A. Langendijk*, Henriette E. Westerlaan, Tara A. van de Water, Hendrik P. Bijl

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

109 Citations (Scopus)

Abstract

Background and purpose: Radiotherapy, alone or combined with chemotherapy, is a treatment modality used frequently in head and neck cancer. In order to report, compare and interpret the sequelae of radiation treatment adequately, it is important to delineate organs at risk (OARs) according to well-defined and uniform guidelines. The aim of this paper was to present our institutional Computed Tomography (CT)-based delineation guidelines for organs in the head and neck at risk for radiation-induced swallowing dysfunction (SWOARs).

Material and methods: After analyses of the human anatomy of the head and neck area and literature review, CT-based guidelines for delineation of the most relevant SWOARs were described by a panel of experts.

Results and conclusions: This paper described institutional guidelines for the delineation of potential SWOARs, accompanied by CT-based illustrations presenting examples of the delineated structures and their corresponding anatomic borders. This paper is essential to ensure adequate interpretation of future reports on the relationship between dose distribution in these SWOARs and different aspects of post-treatment swallowing dysfunction. (C) 2011 Elsevier Ireland Ltd. All rights reserved. Radiotherapy and Oncology 101 (2011) 394-402

Original languageEnglish
Pages (from-to)394-402
Number of pages9
JournalRadiotherapy and Oncology
Volume101
Issue number3
DOIs
Publication statusPublished - Dec-2011

Keywords

  • Head and neck cancer
  • Radiotherapy
  • Organs at risk
  • Swallowing dysfunction
  • Dysphagia
  • INTENSITY-MODULATED RADIOTHERAPY
  • QUALITY-OF-LIFE
  • NECK-CANCER PATIENTS
  • SQUAMOUS-CELL CARCINOMA
  • NASOPHARYNGEAL CARCINOMA
  • PROXIMAL ESOPHAGUS
  • RADIATION-THERAPY
  • ADVANCED HEAD
  • DYSPHAGIA
  • CHEMORADIATION

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