Design and synthesis of multifunctional phospholipids

E Drakopoulou; GM Tsivgoulis; A Mukhopadhyay; A Brisson

Design and synthesis of multifunctional phospholipids

E Drakopoulou^*
, GM Tsivgoulis
, A Mukhopadhyay
, A Brisson

^*Corresponding author for this work

Polymer Chemistry and Bioengineering

Research output: Contribution to journal › Article › Academic › peer-review

8 Citations (Scopus)

Abstract

The synthesis of a bifunctionalized phosholipid capable of binding streptavidin or poly-histidine-tagged proteins is reported for the first time. The head group containing both a biotin and an NTA chelator is synthesized via a new approach using solid phase synthesis. (C) 2000 Elsevier Science Ltd. All rights reserved.

Original language	English
Pages (from-to)	4131-4134
Number of pages	4
Journal	Tetrahedron Letters
Volume	41
Issue number	21
Publication status	Published - 29-May-2000

Keywords

solid phase synthesis
molecular recognition
phospholipids
nickel-chelators
biotin
HELICAL CRYSTALLIZATION
PROTEINS
PEPTIDES
LIPIDS

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@article{18df976157f04e089b03ac045a78e128,

title = "Design and synthesis of multifunctional phospholipids",

abstract = "The synthesis of a bifunctionalized phosholipid capable of binding streptavidin or poly-histidine-tagged proteins is reported for the first time. The head group containing both a biotin and an NTA chelator is synthesized via a new approach using solid phase synthesis. (C) 2000 Elsevier Science Ltd. All rights reserved.",

keywords = "solid phase synthesis, molecular recognition, phospholipids, nickel-chelators, biotin, HELICAL CRYSTALLIZATION, PROTEINS, PEPTIDES, LIPIDS",

author = "E Drakopoulou and GM Tsivgoulis and A Mukhopadhyay and A Brisson",

year = "2000",

month = may,

day = "29",

language = "English",

volume = "41",

pages = "4131--4134",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "PERGAMON-ELSEVIER SCIENCE LTD",

number = "21",

}

TY - JOUR

T1 - Design and synthesis of multifunctional phospholipids

AU - Drakopoulou, E

AU - Tsivgoulis, GM

AU - Mukhopadhyay, A

AU - Brisson, A

PY - 2000/5/29

Y1 - 2000/5/29

N2 - The synthesis of a bifunctionalized phosholipid capable of binding streptavidin or poly-histidine-tagged proteins is reported for the first time. The head group containing both a biotin and an NTA chelator is synthesized via a new approach using solid phase synthesis. (C) 2000 Elsevier Science Ltd. All rights reserved.

AB - The synthesis of a bifunctionalized phosholipid capable of binding streptavidin or poly-histidine-tagged proteins is reported for the first time. The head group containing both a biotin and an NTA chelator is synthesized via a new approach using solid phase synthesis. (C) 2000 Elsevier Science Ltd. All rights reserved.

KW - solid phase synthesis

KW - molecular recognition

KW - phospholipids

KW - nickel-chelators

KW - biotin

KW - HELICAL CRYSTALLIZATION

KW - PROTEINS

KW - PEPTIDES

KW - LIPIDS

M3 - Article

SN - 0040-4039

VL - 41

SP - 4131

EP - 4134

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 21

ER -

Design and synthesis of multifunctional phospholipids

Abstract

Keywords

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