Desosamine in multicomponent reactions

Sepp Achatz, Alexander Dömling

Research output: Contribution to journalArticleAcademicpeer-review

23 Citations (Scopus)

Abstract

Desosamine occurring ubiquitously in natural products is introduced into isocyanide based multicomponent reaction chemistry. Corresponding products are of potential interest for the design of novel antibiotics. © 2006.
Original languageEnglish
Pages (from-to)6360-6362
Number of pages3
JournalBioorganic and Medicinal Chemistry Letters
Volume16
Issue number24
DOIs
Publication statusPublished - 15-Dec-2006

Keywords

  • Antibiotic
  • Desosamine
  • Isocyanide
  • Multicomponent reaction
  • Ribosome
  • Tetrazole
  • 2 aminodesosamine
  • cyanide
  • erythromycin
  • natural product
  • unclassified drug
  • aminolysis
  • article
  • chemical reaction
  • combinatorial chemistry
  • drug design
  • drug hydrolysis
  • drug structure
  • drug synthesis
  • hydrogen bond
  • structure analysis

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