Abstract
The uptake of 2-deoxy-2-[F-18]fluoro-D-glucose (FDG) in neck lymph nodes of twelve patients with a squamous-cell carcinoma of the oral cavity was studied with PET in order to detect and locate lymphogenic metastases. Methods: The results of FDG-PET imaging were compared with clinical, MRI and histopathologic findings. Standardized uptake values (SUV) were also calculated. Results: A sensitivity of 91% and a specificity of 88% were calculated for FDG-PET. In contrast, a sensitivity of 36% and a specificity of 94% were calculated for MRI. Calculated SUVs for reactive lymph nodes, metastatic lymph nodes and the primary tumor were undifferentiated. Conclusion: Using FDG-PET, lymph node metastases of squamous-cell carcinomas of the oral cavity can be visualized with a high sensitivity and specificity. FDG-PET can be an improvement in the evaluation of the neck.
| Original language | English |
|---|---|
| Pages (from-to) | 211-216 |
| Number of pages | 6 |
| Journal | Journal of Nuclear Medicine |
| Volume | 36 |
| Issue number | 2 |
| Publication status | Published - Feb-1995 |
Keywords
- PET
- FLUORODEOXYGLUCOSE
- MRI
- HEAD AND NECK METASTASES
- POSITRON EMISSION TOMOGRAPHY
- F-18 FLUORODEOXYGLUCOSE
- INTRATUMORAL DISTRIBUTION
- FLOW-CYTOMETRY
- TUMORS
- TISSUES
- INVIVO
- BRAIN