Development and evaluation of an online three-level proton vs photon decision support prototype for head and neck cancer - Comparison of dose, toxicity and cost-effectiveness

Qing Cheng; Erik Roelofs; Bram L. T. Ramaekers; Danielle Eekers; Johan van Soest; Tim Lustberg; Tim Hendriks; Frank Hoebers; Hans Paul van der Laan; Erik W. Korevaar; Andre Dekker; Johannes A. Langendijk; Philippe Lambin

doi:10.1016/j.radonc.2015.12.029

Development and evaluation of an online three-level proton vs photon decision support prototype for head and neck cancer - Comparison of dose, toxicity and cost-effectiveness

Qing Cheng, Erik Roelofs, Bram L. T. Ramaekers, Danielle Eekers, Johan van Soest, Tim Lustberg, Tim Hendriks, Frank Hoebers, Hans Paul van der Laan, Erik W. Korevaar, Andre Dekker, Johannes A. Langendijk, Philippe Lambin^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

To quantitatively assess the effectiveness of proton therapy for individual patients, we developed a prototype for an online platform for proton decision support (PRODECIS) comparing photon and proton treatments on dose metric, toxicity and cost-effectiveness levels. An evaluation was performed with 23 head and neck cancer datasets. (C) 2016 The Authors. Published by Elsevier Ireland Ltd.

Original language	English
Pages (from-to)	281-285
Number of pages	5
Journal	Radiotherapy and Oncology
Volume	118
Issue number	2
DOIs	https://doi.org/10.1016/j.radonc.2015.12.029
Publication status	Published - Feb-2016

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Development and evaluation of an online three-level proton vs photon decision support prototype for head and neck cancer – Comparison of dose, toxicity and cost-effectivenessFinal publisher's version, 525 KBLicence: CC BY-NC-ND

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Cheng, Q., Roelofs, E., Ramaekers, B. L. T., Eekers, D., van Soest, J., Lustberg, T., Hendriks, T., Hoebers, F., van der Laan, H. P., Korevaar, E. W., Dekker, A., Langendijk, J. A., & Lambin, P. (2016). Development and evaluation of an online three-level proton vs photon decision support prototype for head and neck cancer - Comparison of dose, toxicity and cost-effectiveness. Radiotherapy and Oncology, 118(2), 281-285. https://doi.org/10.1016/j.radonc.2015.12.029

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title = "Development and evaluation of an online three-level proton vs photon decision support prototype for head and neck cancer - Comparison of dose, toxicity and cost-effectiveness",

abstract = "To quantitatively assess the effectiveness of proton therapy for individual patients, we developed a prototype for an online platform for proton decision support (PRODECIS) comparing photon and proton treatments on dose metric, toxicity and cost-effectiveness levels. An evaluation was performed with 23 head and neck cancer datasets. (C) 2016 The Authors. Published by Elsevier Ireland Ltd.",

author = "Qing Cheng and Erik Roelofs and Ramaekers, \{Bram L. T.\} and Danielle Eekers and \{van Soest\}, Johan and Tim Lustberg and Tim Hendriks and Frank Hoebers and \{van der Laan\}, \{Hans Paul\} and Korevaar, \{Erik W.\} and Andre Dekker and Langendijk, \{Johannes A.\} and Philippe Lambin",

year = "2016",

month = feb,

doi = "10.1016/j.radonc.2015.12.029",

language = "English",

volume = "118",

pages = "281--285",

journal = "Radiotherapy and Oncology",

issn = "0167-8140",

publisher = "ELSEVIER IRELAND LTD",

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Cheng, Q, Roelofs, E, Ramaekers, BLT, Eekers, D, van Soest, J, Lustberg, T, Hendriks, T, Hoebers, F, van der Laan, HP , Korevaar, EW, Dekker, A, Langendijk, JA & Lambin, P 2016, 'Development and evaluation of an online three-level proton vs photon decision support prototype for head and neck cancer - Comparison of dose, toxicity and cost-effectiveness', Radiotherapy and Oncology, vol. 118, no. 2, pp. 281-285. https://doi.org/10.1016/j.radonc.2015.12.029

Development and evaluation of an online three-level proton vs photon decision support prototype for head and neck cancer - Comparison of dose, toxicity and cost-effectiveness. / Cheng, Qing; Roelofs, Erik; Ramaekers, Bram L. T. et al.
In: Radiotherapy and Oncology, Vol. 118, No. 2, 02.2016, p. 281-285.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Development and evaluation of an online three-level proton vs photon decision support prototype for head and neck cancer - Comparison of dose, toxicity and cost-effectiveness

AU - Cheng, Qing

AU - Roelofs, Erik

AU - Ramaekers, Bram L. T.

AU - Eekers, Danielle

AU - van Soest, Johan

AU - Lustberg, Tim

AU - Hendriks, Tim

AU - Hoebers, Frank

AU - van der Laan, Hans Paul

AU - Korevaar, Erik W.

AU - Dekker, Andre

AU - Langendijk, Johannes A.

AU - Lambin, Philippe

PY - 2016/2

Y1 - 2016/2

N2 - To quantitatively assess the effectiveness of proton therapy for individual patients, we developed a prototype for an online platform for proton decision support (PRODECIS) comparing photon and proton treatments on dose metric, toxicity and cost-effectiveness levels. An evaluation was performed with 23 head and neck cancer datasets. (C) 2016 The Authors. Published by Elsevier Ireland Ltd.

AB - To quantitatively assess the effectiveness of proton therapy for individual patients, we developed a prototype for an online platform for proton decision support (PRODECIS) comparing photon and proton treatments on dose metric, toxicity and cost-effectiveness levels. An evaluation was performed with 23 head and neck cancer datasets. (C) 2016 The Authors. Published by Elsevier Ireland Ltd.

U2 - 10.1016/j.radonc.2015.12.029

DO - 10.1016/j.radonc.2015.12.029

M3 - Article

C2 - 26924342

SN - 0167-8140

VL - 118

SP - 281

EP - 285

JO - Radiotherapy and Oncology

JF - Radiotherapy and Oncology

IS - 2

ER -

Development and evaluation of an online three-level proton vs photon decision support prototype for head and neck cancer - Comparison of dose, toxicity and cost-effectiveness

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