TY - JOUR
T1 - Development and Validation of an Abbreviated Questionnaire to Easily Measure Cognitive Failure in ICU Survivors
T2 - A Multicenter Study
AU - Wassenaar, Annelies
AU - De Reus, Jorn
AU - Donders, A. Rogier T.
AU - Schoonhoven, Lisette
AU - Cremer, Olaf L.
AU - De Lange, Dylan W.
AU - Van Dijk, Diederik
AU - Slooter, Arjen J.C.
AU - Pickkers, Peter
AU - Van Den Boogaard, Mark
N1 - Publisher Copyright:
© 2017 by the Society of Critical Care Medicine and Wolters Kluwer Health, Inc. All Rights Reserved.
PY - 2018/1/1
Y1 - 2018/1/1
N2 - Objectives: To develop and validate an abbreviated version of the Cognitive Failure Questionnaire that can be used by patients as part of self-assessment to measure functional cognitive outcome in ICU survivors.Design: A retrospective multicenter observational study.Setting: The ICUs of two Dutch university hospitals.Patients: Adult ICU survivors.Interventions: None.Measurements and Main Results: Cognitive functioning was evaluated between 12 and 24 months after ICU discharge using the full 25-item Cognitive Failure Questionnaire (CFQ-25). Incomplete CFQ-25 questionnaires were excluded from analysis. Forward selection in a linear regression model was used in hospital A to assess which of the CFQ-25 items should be included to prevent a significant loss of correlation between an abbreviated and the full CFQ-25. Subsequently, the performance of an abbreviated Cognitive Failure Questionnaire was determined in hospital B using Pearson's correlation. A Bland-Altman plot was used to examine whether the reduced-item outcome scores of an abbreviated Cognitive Failure Questionnaire were a replacement for the full CFQ-25 outcome scores. Among 1,934 ICU survivors, 1,737 were included, 819 in hospital A, 918 in hospital B. The Pearson's correlation between the abbreviated 14-item Cognitive Failure Questionnaire (CFQ-14) and the CFQ-25 was 0.99. The mean of the difference scores was-0.26, and 95% of the difference scores fell within +5 and-5.5 on a 100-point maximum score.Conclusions: It is feasible to use the abbreviated CFQ-14 to measure self-reported cognitive failure in ICU survivors as this questionnaire has a similar performance as the full CFQ-25.
AB - Objectives: To develop and validate an abbreviated version of the Cognitive Failure Questionnaire that can be used by patients as part of self-assessment to measure functional cognitive outcome in ICU survivors.Design: A retrospective multicenter observational study.Setting: The ICUs of two Dutch university hospitals.Patients: Adult ICU survivors.Interventions: None.Measurements and Main Results: Cognitive functioning was evaluated between 12 and 24 months after ICU discharge using the full 25-item Cognitive Failure Questionnaire (CFQ-25). Incomplete CFQ-25 questionnaires were excluded from analysis. Forward selection in a linear regression model was used in hospital A to assess which of the CFQ-25 items should be included to prevent a significant loss of correlation between an abbreviated and the full CFQ-25. Subsequently, the performance of an abbreviated Cognitive Failure Questionnaire was determined in hospital B using Pearson's correlation. A Bland-Altman plot was used to examine whether the reduced-item outcome scores of an abbreviated Cognitive Failure Questionnaire were a replacement for the full CFQ-25 outcome scores. Among 1,934 ICU survivors, 1,737 were included, 819 in hospital A, 918 in hospital B. The Pearson's correlation between the abbreviated 14-item Cognitive Failure Questionnaire (CFQ-14) and the CFQ-25 was 0.99. The mean of the difference scores was-0.26, and 95% of the difference scores fell within +5 and-5.5 on a 100-point maximum score.Conclusions: It is feasible to use the abbreviated CFQ-14 to measure self-reported cognitive failure in ICU survivors as this questionnaire has a similar performance as the full CFQ-25.
KW - cognitive dysfunction
KW - cognitive failure questionnaire
KW - intensive care unit
KW - neuropsychologic tests
KW - postintensive care syndrome
UR - https://www.scopus.com/pages/publications/85038220205
U2 - 10.1097/CCM.0000000000002806
DO - 10.1097/CCM.0000000000002806
M3 - Article
C2 - 29068855
AN - SCOPUS:85038220205
SN - 0090-3493
VL - 46
SP - 79
EP - 84
JO - Critical Care Medicine
JF - Critical Care Medicine
IS - 1
ER -