Differential associations between depressive symptoms and glycaemic control in outpatients with diabetes

M. Bot*, F. Pouwer, P. de Jonge, C. J. Tack, P. H. L. M. Geelhoed-Duijvestijn, F. J. Snoek

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

Aims Depression is common in people with diabetes, and related to higher HbA1c levels. Depression, however, is a heterogeneous construct that involves a variety of symptoms. As little is known about the associations of individual depressive symptoms with HbA1c, we explored these associations in outpatients with diabetes. Methods The study was conducted in three tertiary diabetes clinics in the Netherlands. At baseline, the presence of the nine depressive symptoms that are listed in the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition was assessed with the nine-item Patient Health Questionnaire (PHQ-9). At baseline and after a 1-year follow-up, HbA1c was derived from the medical charts. Results A total of 288 out of 646 subjects with diabetes (45%) reported one or more depressive symptom(s). Depressed mood (=0.11, P=0.005), sleeping difficulties (=0.16, P

Original languageEnglish
Pages (from-to)E115-E122
Number of pages8
JournalDiabetic Medicine
Volume30
Issue number3
DOIs
Publication statusPublished - Mar-2013

Keywords

  • CO-MORBID DEPRESSION
  • SLEEP DURATION
  • TYPE-1
  • PREVALENCE
  • COMPLICATIONS
  • MELLITUS
  • ADULTS
  • METAANALYSIS
  • SEVERITY
  • RISK

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