Abstract
This thesis describes our efforts to develop inhibitors using combinatorial-chemistry approaches. These approaches can potentially speed-up the drug discovery trajectory and the discovered molecules could be used as starting points for future drug development projects targeting 15-LOX-1, MIF and/or MDM2. The aforementioned targets are all proteins that play an important role in common diseases.
Original language | English |
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Qualification | Doctor of Philosophy |
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Award date | 27-Nov-2020 |
Place of Publication | [Groningen] |
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Publication status | Published - 2020 |