Distant metastases from head and neck squamous cell carcinoma. Part III. Treatment

Missak Haigentz; Dana M. Hartl; Carl E. Silver; Johannes A. Langendijk; Primoz Strojan; Vinidh Paleri; Remco de Bree; Jean-Pascal Machiels; Marc Hamoir; Alessandra Rinaldo; Daniela Paccagnella; Ashok R. Shaha; Robert P. Takes; Alfio Ferlito

doi:10.1016/j.oraloncology.2012.03.019

Distant metastases from head and neck squamous cell carcinoma. Part III. Treatment

Missak Haigentz, Dana M. Hartl, Carl E. Silver, Johannes A. Langendijk, Primoz Strojan, Vinidh Paleri, Remco de Bree, Jean-Pascal Machiels, Marc Hamoir, Alessandra Rinaldo, Daniela Paccagnella, Ashok R. Shaha, Robert P. Takes, Alfio Ferlito^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

47 Citations (Scopus)

Abstract

Distant metastases from head and neck squamous cell carcinoma (HNSCC), though rare at initial presentation, remain an important manifestation of cancer recurrence and mortality. Although generally considered incurable with a dismal prognosis despite palliative therapy, highly selected patients with distant metastases may have a long term survival benefit from aggressive surgery or radiotherapy. Advances in systemic treatments also may improve patient survival. This article reviews the current state of management of HNSCC patients with distant metastases. (C) 2012 Elsevier Ltd. All rights reserved.

Original language	English
Pages (from-to)	787-793
Number of pages	7
Journal	Oral Oncology
Volume	48
Issue number	9
DOIs	https://doi.org/10.1016/j.oraloncology.2012.03.019
Publication status	Published - Sept-2012

Keywords

Distant metastases
Head and neck squamous cell carcinoma
Treatment
Chemotherapy
Metastasectomy
PLATINUM-BASED CHEMOTHERAPY
COOPERATIVE-ONCOLOGY-GROUP
CISPLATIN PLUS FLUOROURACIL
PULMONARY METASTASES
PHASE-II
RADIOFREQUENCY ABLATION
SURGICAL RESECTION
LARYNGEAL-CANCER
RANDOMIZED-TRIAL
SOLID TUMORS

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Haigentz, M., Hartl, D. M., Silver, C. E., Langendijk, J. A., Strojan, P., Paleri, V., de Bree, R., Machiels, J.-P., Hamoir, M., Rinaldo, A., Paccagnella, D., Shaha, A. R., Takes, R. P., & Ferlito, A. (2012). Distant metastases from head and neck squamous cell carcinoma. Part III. Treatment. Oral Oncology, 48(9), 787-793. https://doi.org/10.1016/j.oraloncology.2012.03.019

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title = "Distant metastases from head and neck squamous cell carcinoma. Part III. Treatment",

abstract = "Distant metastases from head and neck squamous cell carcinoma (HNSCC), though rare at initial presentation, remain an important manifestation of cancer recurrence and mortality. Although generally considered incurable with a dismal prognosis despite palliative therapy, highly selected patients with distant metastases may have a long term survival benefit from aggressive surgery or radiotherapy. Advances in systemic treatments also may improve patient survival. This article reviews the current state of management of HNSCC patients with distant metastases. (C) 2012 Elsevier Ltd. All rights reserved.",

keywords = "Distant metastases, Head and neck squamous cell carcinoma, Treatment, Chemotherapy, Metastasectomy, PLATINUM-BASED CHEMOTHERAPY, COOPERATIVE-ONCOLOGY-GROUP, CISPLATIN PLUS FLUOROURACIL, PULMONARY METASTASES, PHASE-II, RADIOFREQUENCY ABLATION, SURGICAL RESECTION, LARYNGEAL-CANCER, RANDOMIZED-TRIAL, SOLID TUMORS",

author = "Missak Haigentz and Hartl, {Dana M.} and Silver, {Carl E.} and Langendijk, {Johannes A.} and Primoz Strojan and Vinidh Paleri and {de Bree}, Remco and Jean-Pascal Machiels and Marc Hamoir and Alessandra Rinaldo and Daniela Paccagnella and Shaha, {Ashok R.} and Takes, {Robert P.} and Alfio Ferlito",

year = "2012",

month = sep,

doi = "10.1016/j.oraloncology.2012.03.019",

language = "English",

volume = "48",

pages = "787--793",

journal = "Oral Oncology",

issn = "1368-8375",

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TY - JOUR

T1 - Distant metastases from head and neck squamous cell carcinoma. Part III. Treatment

AU - Haigentz, Missak

AU - Hartl, Dana M.

AU - Silver, Carl E.

AU - Langendijk, Johannes A.

AU - Strojan, Primoz

AU - Paleri, Vinidh

AU - de Bree, Remco

AU - Machiels, Jean-Pascal

AU - Hamoir, Marc

AU - Rinaldo, Alessandra

AU - Paccagnella, Daniela

AU - Shaha, Ashok R.

AU - Takes, Robert P.

AU - Ferlito, Alfio

PY - 2012/9

Y1 - 2012/9

N2 - Distant metastases from head and neck squamous cell carcinoma (HNSCC), though rare at initial presentation, remain an important manifestation of cancer recurrence and mortality. Although generally considered incurable with a dismal prognosis despite palliative therapy, highly selected patients with distant metastases may have a long term survival benefit from aggressive surgery or radiotherapy. Advances in systemic treatments also may improve patient survival. This article reviews the current state of management of HNSCC patients with distant metastases. (C) 2012 Elsevier Ltd. All rights reserved.

AB - Distant metastases from head and neck squamous cell carcinoma (HNSCC), though rare at initial presentation, remain an important manifestation of cancer recurrence and mortality. Although generally considered incurable with a dismal prognosis despite palliative therapy, highly selected patients with distant metastases may have a long term survival benefit from aggressive surgery or radiotherapy. Advances in systemic treatments also may improve patient survival. This article reviews the current state of management of HNSCC patients with distant metastases. (C) 2012 Elsevier Ltd. All rights reserved.

KW - Distant metastases

KW - Head and neck squamous cell carcinoma

KW - Treatment

KW - Chemotherapy

KW - Metastasectomy

KW - PLATINUM-BASED CHEMOTHERAPY

KW - COOPERATIVE-ONCOLOGY-GROUP

KW - CISPLATIN PLUS FLUOROURACIL

KW - PULMONARY METASTASES

KW - PHASE-II

KW - RADIOFREQUENCY ABLATION

KW - SURGICAL RESECTION

KW - LARYNGEAL-CANCER

KW - RANDOMIZED-TRIAL

KW - SOLID TUMORS

U2 - 10.1016/j.oraloncology.2012.03.019

DO - 10.1016/j.oraloncology.2012.03.019

M3 - Review article

SN - 1368-8375

VL - 48

SP - 787

EP - 793

JO - Oral Oncology

JF - Oral Oncology

IS - 9

ER -

Distant metastases from head and neck squamous cell carcinoma. Part III. Treatment

Abstract

Keywords

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