Objective: To consider the risk of intercourse without contraception during infertility treatment.
Design: Case report.
Setting: Leiden University Medical Center.
Patient(s): An infertile couple underwent IVF for tubal pathology.
Intervention(s): Transfer of one embryo during a natural cycle.
Main Outcome Measure(s): Human leukocyte antigen typing, histochemical analysis of the fetal membranes, neonatal and maternal clinical outcomes.
Result(s): A dizygotic twin pregnancy was confirmed after birth by human leukocyte antigen typing of both fetuses and mother and by histochemical analysis of the dividing fetal membranes. This suggests a pregnancy of concurrent IVF and spontaneous conception. Pregnancy was complicated by preeclampsia and intrauterine growth retardation of both fetuses.
Conclusion(s): We state that couples should abstain from intercourse without contraception during infertility treatment to prevent multiple gestation and its related complications for mother and fetuses. (Fertil Steril (R) 2011;95:805.e1-e3. (C)2011 by American Society for Reproductive Medicine.)
- twin pregnancy
- intercourse without contraception
- QUADRUPLET PREGNANCY