Abstract
Innate immune checkpoint CD47 has emerged as a prominent target for cancer immunotherapy and defining biomarkers predictive of response will be a crucial step towards clinical implementation. Hereto, we investigated the importance of a previously reported requisite for SLAM family member 7(SLAMF7) expression on cancer cell phagocytosis for effective CD47 antibody therapy.
Original language | English |
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Article number | 1600349 |
Number of pages | 3 |
Journal | Molecular and Cellular Oncology |
Volume | 6 |
Issue number | 3 |
DOIs |
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Publication status | Published - 1-Jan-2019 |
Keywords
- CD47
- DLBCL
- phagocytosis
- SLAMF7