Does cancer cell-expressed SLAMF7 impact on CD47-mediated phagocytosis?

Renee Bouwstra; Tom van Meerten; Edwin Bremer

doi:10.1080/23723556.2019.1600349

Does cancer cell-expressed SLAMF7 impact on CD47-mediated phagocytosis?

Renee Bouwstra^*, Tom van Meerten, Edwin Bremer

^*Corresponding author for this work

Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review

4 Citations (Scopus)

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Abstract

Innate immune checkpoint CD47 has emerged as a prominent target for cancer immunotherapy and defining biomarkers predictive of response will be a crucial step towards clinical implementation. Hereto, we investigated the importance of a previously reported requisite for SLAM family member 7(SLAMF7) expression on cancer cell phagocytosis for effective CD47 antibody therapy.

Original language	English
Article number	1600349
Number of pages	3
Journal	Molecular and Cellular Oncology
Volume	6
Issue number	3
DOIs	https://doi.org/10.1080/23723556.2019.1600349
Publication status	Published - 1-Jan-2019

Keywords

CD47
DLBCL
phagocytosis
SLAMF7

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10.1080/23723556.2019.1600349

Does cancer cell-expressed SLAMF7 impact on CD47-mediated phagocytosis_Final publisher's version, 768 KBLicence: Taverne

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@article{3748c31123994977a26c7752a709e940,

title = "Does cancer cell-expressed SLAMF7 impact on CD47-mediated phagocytosis?",

abstract = "Innate immune checkpoint CD47 has emerged as a prominent target for cancer immunotherapy and defining biomarkers predictive of response will be a crucial step towards clinical implementation. Hereto, we investigated the importance of a previously reported requisite for SLAM family member 7(SLAMF7) expression on cancer cell phagocytosis for effective CD47 antibody therapy.",

keywords = "CD47, DLBCL, phagocytosis, SLAMF7",

author = "Renee Bouwstra and {van Meerten}, Tom and Edwin Bremer",

year = "2019",

month = jan,

day = "1",

doi = "10.1080/23723556.2019.1600349",

language = "English",

volume = "6",

journal = "Molecular and Cellular Oncology",