There is as yet no clear protocol available for counselling a person who has one or more relatives with Down syndrome of unknown genotype. Counsellors use different approaches based on their own experience. We present a protocol for practical use which can be helpful in making a decision in clinical situations such as those mentioned above. In this protocol we have used a simple formula to calculate an approximate risk for the counsellee of having a child with Down Syndrome due to an as yet unrecognized familial translocation.
|Number of pages||5|
|Publication status||Published - Jun-1996|
- Down syndrome
- risk estimation
- genetic counselling