Dunnelaagchromatografie met dampprogrammering: Ontwikkeling van een nieuwe techniek en enkele toepassingen daarvan

Some unexpected results in thin layer chromatography (TLC) with multicomponent solvents gave us the idea that solvent vapour could play a role in the realization of the separation. This presumption has led to the investigations described in this thesis. By developing TLC plates in the presence of vapour of liquids not present in the running solvent, it could be shown that separations are influenced by the nature and the amount of vapour, adsorbed by the dry adsorbent. Changes in the nature and in the amount of this adsorbed vapour with - identical solvents - cause great changes in the separations. The vapour adsorption processes tend to form an adsorbate as polar as possible with the rate of adsorption being different for each individual vapour component, depending on its own polarity and on the polarity of other available components. The vapour adsorbate, consisting of the more polar vapour components, is to be considered the precursor of the stationary phase which will arise when the running solvent covers these areas impregnated by vapour. It should be noted that when wetted by the solvent, the adsorbent will form an adsorbate consisting of the more polar components of the solvent and the solvent vapour...