Abstract
The inner ear, fluid pressure was measured in scala media of the guinea pig through one barrel of a double-barreled micropipette after a sudden volume increase or decrease, caused by injection or withdrawal of artificial endolymph through the other barrel. During injection or withdrawal, the inner ear pressure changed in the order of 1-10 cm water, but it returned to its initial value within a few seconds. The time constant for the pressure recovery depended on the flow direction. It was on average 1.1 s after a short overpressure and 2.8 s after underpressure. The obtained results could be fitted with a simple physical model, when it was assumed that inner ear pressure recovery is a non-linear process, governed by a pressure-dependent flow resistance and/or membrane compliance. (C) 1999 Elsevier Science B.V. All rights reserved.
Original language | English |
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Pages (from-to) | 131-139 |
Number of pages | 9 |
Journal | Hearing Research |
Volume | 132 |
Issue number | 1-2 |
Publication status | Published - Jun-1999 |
Keywords
- cochlea
- hydrops
- endolymph
- Meniere
- aqueduct
- HYDROSTATIC-PRESSURE
- COCHLEAR AQUEDUCT
- ENDOLYMPHATIC HYDROPS
- ROUND WINDOW
- PERILYMPH
- MEMBRANE
- PATENCY