Dystonie bij cerebrale parese: Wat zijn de behandelopties?

Laura A van de Pol; Laura A Bonouvrié; R Jeroen Vermeulen; Marina A J de Koning-Tijssen; Martje E van Egmond; Michel A Willemsen; Annemieke I Buizer

Dystonie bij cerebrale parese: Wat zijn de behandelopties?

Translated title of the contribution: Dystonia in cerebral palsy; what are the treatment options?

Laura A van de Pol, Laura A Bonouvrié, R Jeroen Vermeulen, Marina A J de Koning-Tijssen, Martje E van Egmond, Michel A Willemsen, Annemieke I Buizer

Biology-Related, Artificial, and Interventional Neuroscience (BRAIN)

Research output: Contribution to journal › Review article › peer-review

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Abstract

Cerebral palsy (CP) is the most common cause of motor disability in children. The largest group of children with CP present with spasticity. Dystonia is estimated to be present in approximately 15% of children with CP, referred to as dyskinetic CP. Still, dystonia in CP remains underdiagnosed. Dystonia and spasticity can occur together in a subgroup of children with CP as well. Dystonia is characterized by fluctuating hypertonia and involuntary movement and postures. Dystonia in children with CP can interfere with motor function, caregiving and comfort. It is important to recognize dystonia in children with CP as specific treatment is indicated. In this paper we describe three cases of children with dystonia in CP and we review the pharmacological treatment options for dystonia in CP and the surgical options including intrathecal baclofen pump and deep brain stimulation.

Translated title of the contribution	Dystonia in cerebral palsy; what are the treatment options?
Original language	Dutch
Article number	D5868
Number of pages	5
Journal	Nederlands Tijdschrift voor Geneeskunde
Volume	166
Publication status	Published - 22-Feb-2022

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@article{33b6691c3ed94cd0b06f2d6dd3838377,

title = "Dystonie bij cerebrale parese: Wat zijn de behandelopties?",

abstract = "Cerebral palsy (CP) is the most common cause of motor disability in children. The largest group of children with CP present with spasticity. Dystonia is estimated to be present in approximately 15% of children with CP, referred to as dyskinetic CP. Still, dystonia in CP remains underdiagnosed. Dystonia and spasticity can occur together in a subgroup of children with CP as well. Dystonia is characterized by fluctuating hypertonia and involuntary movement and postures. Dystonia in children with CP can interfere with motor function, caregiving and comfort. It is important to recognize dystonia in children with CP as specific treatment is indicated. In this paper we describe three cases of children with dystonia in CP and we review the pharmacological treatment options for dystonia in CP and the surgical options including intrathecal baclofen pump and deep brain stimulation.",

keywords = "Cerebral Palsy/drug therapy, Child, Disabled Persons, Dystonia/diagnosis, Dystonic Disorders/diagnosis, Humans, Motor Disorders/complications, Muscle Spasticity",

author = "{van de Pol}, {Laura A} and Bonouvri{\'e}, {Laura A} and Vermeulen, {R Jeroen} and {de Koning-Tijssen}, {Marina A J} and {van Egmond}, {Martje E} and Willemsen, {Michel A} and Buizer, {Annemieke I}",

year = "2022",

month = feb,

day = "22",

language = "Dutch",

volume = "166",

journal = "Nederlands Tijdschrift voor Geneeskunde",

issn = "0028-2162",

publisher = "NLM (Medline)",

}

TY - JOUR

T1 - Dystonie bij cerebrale parese

T2 - Wat zijn de behandelopties?

AU - van de Pol, Laura A

AU - Bonouvrié, Laura A

AU - Vermeulen, R Jeroen

AU - de Koning-Tijssen, Marina A J

AU - van Egmond, Martje E

AU - Willemsen, Michel A

AU - Buizer, Annemieke I

PY - 2022/2/22

Y1 - 2022/2/22

N2 - Cerebral palsy (CP) is the most common cause of motor disability in children. The largest group of children with CP present with spasticity. Dystonia is estimated to be present in approximately 15% of children with CP, referred to as dyskinetic CP. Still, dystonia in CP remains underdiagnosed. Dystonia and spasticity can occur together in a subgroup of children with CP as well. Dystonia is characterized by fluctuating hypertonia and involuntary movement and postures. Dystonia in children with CP can interfere with motor function, caregiving and comfort. It is important to recognize dystonia in children with CP as specific treatment is indicated. In this paper we describe three cases of children with dystonia in CP and we review the pharmacological treatment options for dystonia in CP and the surgical options including intrathecal baclofen pump and deep brain stimulation.

AB - Cerebral palsy (CP) is the most common cause of motor disability in children. The largest group of children with CP present with spasticity. Dystonia is estimated to be present in approximately 15% of children with CP, referred to as dyskinetic CP. Still, dystonia in CP remains underdiagnosed. Dystonia and spasticity can occur together in a subgroup of children with CP as well. Dystonia is characterized by fluctuating hypertonia and involuntary movement and postures. Dystonia in children with CP can interfere with motor function, caregiving and comfort. It is important to recognize dystonia in children with CP as specific treatment is indicated. In this paper we describe three cases of children with dystonia in CP and we review the pharmacological treatment options for dystonia in CP and the surgical options including intrathecal baclofen pump and deep brain stimulation.

KW - Cerebral Palsy/drug therapy

KW - Child

KW - Disabled Persons

KW - Dystonia/diagnosis

KW - Dystonic Disorders/diagnosis

KW - Humans

KW - Motor Disorders/complications

KW - Muscle Spasticity

M3 - Review article

C2 - 35499589

SN - 0028-2162

VL - 166

JO - Nederlands Tijdschrift voor Geneeskunde

JF - Nederlands Tijdschrift voor Geneeskunde

M1 - D5868

ER -

Dystonie bij cerebrale parese: Wat zijn de behandelopties?

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