Abstract
Background: Haemodialysis patients have a high risk of malnutrition which is associated with increased mortality. Nocturnal haemodialysis (NHD) is associated with a significant increase in protein intake compared with conventional haemodialysis (CHD). It is unclear whether this leads to improved nutritional status. Therefore, we studied whether 1 year of NHD is associated with a change in body composition. Methods: Whole-body composition using dual-energy X-ray absorptiometry (DEXA) and normalised protein catabolic rate (nPCR) were measured in 11 adult patients before and 1 year after the transition from CHD (12 h dialysis/week) to NHD (28-48 h dialysis/week). Similar measurements were performed in a matched control group of 13 patients who stayed on CHD. Differences between groups were analysed with linear mixed models. Results: At baseline, nPCR, total mass, fat-free mass, and fat mass did not differ significantly between the CHD and NHD groups. nPCR increased in the NHD group (from 0.96 +/- 0.23 to 1.12 +/- 0.20 g/kg/day; p = 0.027) whereas it was stable in the CHD group (0.93 +/- 0.21 at baseline and 0.87 +/- 0.09 g/kg/day at 1 year, n.s.). The change in nPCR differed significantly between the two groups (p = 0.027). We observed no significant differences in the course of total mass, fat-free mass, and fat mass during the 1-year observation period between the NHD and CHD groups. Conclusions: One year of NHD had no significant effect on body composition in comparison with CHD, despite a significantly higher protein intake in patients on NHD. (C) 2014 S. Karger AG, Basel
Original language | English |
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Pages (from-to) | 171-177 |
Number of pages | 7 |
Journal | Nephron clinical practice |
Volume | 128 |
Issue number | 1-2 |
DOIs | |
Publication status | Published - Dec-2014 |
Keywords
- Body composition
- Haemodialysis
- Malnutrition
- Nocturnal home haemodialysis
- Nutritional intake
- Protein intake
- NUTRITIONAL-STATUS
- FREQUENT HEMODIALYSIS
- HOME HEMODIALYSIS
- PHYSICAL FUNCTION
- PROTEIN-INTAKE
- PREDICTORS
- SURVIVAL
- DISEASE
- MUSCLE
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Supplementary Material for: Effect of Nocturnal Haemodialysis on Body Composition
De Jong, P. E. (Contributor), van der Schans, C. (Contributor), Gaillard, C. A. J. M. (Contributor), Slart, R. H. J. A. (Contributor), Krijnen, W. P. (Contributor), Ipema, K. J. R. (Contributor), Franssen, C. (Contributor) & Westerhuis, R. (Contributor), University of Groningen, 12-Oct-2017
DOI: 10.6084/m9.figshare.5492839.v1, https://doi.org/10.6084%2Fm9.figshare.5492839.v1
Dataset
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Supplementary Material for: Effect of Nocturnal Haemodialysis on Body Composition
Ipema, K. (Contributor), Westerhuis, R. (Creator), Van Der Schans, C. P. (Creator), De Jong, P. E. (Creator), Gaillard, C. A. J. M. (Contributor), Krijnen, W. P. (Creator), Slart, R. H. J. A. (Contributor) & Franssen, C. (Contributor), figshare, 12-Oct-2017
DOI: 10.6084/m9.figshare.5492839
Dataset