TY - JOUR
T1 - Effect on hepatic ornithine decarboxylase of some food additives and synthetic elastomers
AU - Kunnen, R
AU - Uijtewaal, B
AU - van Wijk, R
AU - Bisschop, A
AU - Jacobus Mgn Van De Zande, Louis
PY - 1986
Y1 - 1986
N2 - he food additives butylated hydroxytoluene, butylated hydroxyanisole and sodium cyclamate and the precursors for packaging materials acrylamide, acrylic acid, acrylonitrile and vinylpyrrolidone were investigated for their ability to induce hepatic ornithine decarboxylase (ODC) in vivo in order to obtain indications about their possible tumour‐promoting activities. It was shown that butylated hydroxyanisole, acrylonitrile, vinylpyrrolidone and acrylamide have the capacity to increase rat liver ODC activity, while butylated hydroxytoluene, acrylic acid and sodium cyclamate did not affect ODC activity.
AB - he food additives butylated hydroxytoluene, butylated hydroxyanisole and sodium cyclamate and the precursors for packaging materials acrylamide, acrylic acid, acrylonitrile and vinylpyrrolidone were investigated for their ability to induce hepatic ornithine decarboxylase (ODC) in vivo in order to obtain indications about their possible tumour‐promoting activities. It was shown that butylated hydroxyanisole, acrylonitrile, vinylpyrrolidone and acrylamide have the capacity to increase rat liver ODC activity, while butylated hydroxytoluene, acrylic acid and sodium cyclamate did not affect ODC activity.
U2 - 10.1080/02652038609373565
DO - 10.1080/02652038609373565
M3 - Article
C2 - 3956794
VL - 3
SP - 57
EP - 62
JO - Food Additives and Contaminants
JF - Food Additives and Contaminants
SN - 0265-203X
IS - 1
ER -