Abstract
OBJECTIVE: To study the effect of omega-3 polyunsaturated fatty acid supplementation on lipid profile in hypertriglyceridaemic patients.
SETTING: General practice.
DESIGN: Prospective, double blind study of 12 weeks' duration.
PATIENTS AND METHODS: Eight patients received fish oil (1800 mg C20: 5 omega-3 eicosapentaenoic acid (EPA) and 1200 mg C22:6 omega-3 docosahexaenoic acid (DHA). Nine patients received corn oil (3000 mg C18: 2 omega-6 linoleic acid daily).
RESULTS: Lipid profile analysis showed a decrease in triglyceride levels after fish oil supplementation. An unexpected and unexplained finding was the rise in total cholesterol and LDH cholesterol with corn oil supplementation.
CONCLUSION: Fish oil causes a decrease in triglyceride levels in hypertriglyceridaemic patients.
| Translated title of the contribution | Effect of short-term use of omega-3-type polyunsaturated fatty acids in subjects with hypertriglyceridemia |
|---|---|
| Original language | Dutch |
| Pages (from-to) | 1511-1514 |
| Number of pages | 4 |
| Journal | Nederlands Tijdschrift voor Geneeskunde |
| Volume | 136 |
| Issue number | 31 |
| Publication status | Published - 1-Aug-1992 |