Abstract
BACKGROUND AND OBJECTIVES: We excised cutaneous squamous cell carcinoma (cSCC) of the face while using intra-operative frozen section analysis of the margins in an optimized bread-loafing fashion (WIFSA).
METHODS: Medical records were reviewed of 160 cSCCs of the face that were treated by surgical excision with WIFSA between April 2007 and January 2013. The accuracy of WIFSA was verified by comparing results with postoperative formalin-fixed paraffin-embedded (FFPE) sections. Also, recurrence and metastasis during follow-up were studied and duration of treatment and complications were analyzed.
RESULTS: The 160 cSCCs affected 152 patients. In 131 cSCCs (mean follow-up: 41.0 months, SD: ±26.3, range: 3.0-110.7) occurred 6 (4.6%) recurrences and 2 (1.5%) metastases. Of the WIFSA results, 98.8% corresponded with postoperative FFPE sections. Mean duration of treatment was 77 min (SD: ±25, range: 34-159) and complication rate was 8.1%.
CONCLUSIONS: Surgical excision with WIFSA is an excellent treatment modality for cSCC of the face because of its accurate method for assessment of complete tumor removal, low recurrence and metastasis rate, short average duration of treatment, and low complication rate.
| Original language | English |
|---|---|
| Pages (from-to) | 473-478 |
| Number of pages | 6 |
| Journal | Journal of Surgical Oncology |
| Volume | 117 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 1-Mar-2018 |
| Externally published | Yes |
Keywords
- Aged
- Carcinoma, Squamous Cell
- Facial Neoplasms
- Female
- Frozen Sections
- Humans
- Male
- Margins of Excision
- Monitoring, Intraoperative
- Neoplasm Recurrence, Local
- Retrospective Studies
- Skin Neoplasms
- Treatment Outcome
- Journal Article
- MANAGEMENT
- RECURRENCE
- MOHS MICROGRAPHIC SURGERY
- RISK-FACTORS
- SKIN-CANCER
- SURGICAL EXCISION
- BASAL
- METASTASIS