Effects of chlorhexidine oral decontamination on respiratory colonization during mechanical ventilation in intensive care unit patients

  • Douwe F Postma*
  • , Sanjay U C Sankatsing
  • , Steven F T Thijsen
  • , Henrik Endeman
  • *Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)

Abstract

We conducted a retrospective cohort study to assess respiratory colonization before and after the use of chlorhexidine oral decontamination among a cohort of intensive care unit patients who received mechanical ventilation. We observed a decrease in the prevalence of Enterobacteriaceae and an increase in the incidence of fungal colonization. Chlorhexidine oral decontamination might have a differential effect on respiratory colonization.

Original languageEnglish
Pages (from-to)527-30
Number of pages4
JournalInfection control and hospital epidemiology
Volume33
Issue number5
DOIs
Publication statusPublished - 2012
Externally publishedYes

Keywords

  • Aged
  • Aged, 80 and over
  • Bacteria/drug effects
  • Chlorhexidine/administration & dosage
  • Decontamination/methods
  • Equipment Contamination
  • Female
  • Hospitals, Teaching
  • Humans
  • Male
  • Middle Aged
  • Mouthwashes/administration & dosage
  • Netherlands
  • Respiration, Artificial/instrumentation
  • Retrospective Studies

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