EFFECTS OF LOCAL NERVE COOLING ON CONDUCTION IN VAGAL FIBERS SHED LIGHT UPON RESPIRATORY REFLEXES IN THE RABBIT

WR PATBERG*, A NIJMEIJER, A VERSPRILLE, JP ZOCK, WG ZIJLSTRA, J.K. Schut

*Corresponding author for this work

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

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Abstract

In ten vagus nerves the effect of local cooling on the compound action potential was studied in the temperature range of 34 to 0-degrees-C in spontaneously breathing, anaesthetized rabbits. The mean temperature at which the myelinated (A) fibres were completely blocked, was 10.2 +/- 2.4-degrees-C (mean +/- S.D.). In nine nerves, local vagus cooling to 0-degrees-C failed to block all non-myelinated (C) fibres. In one nerve, total blocking occurred at 2.0-degrees-C. We conclude that in the rabbit, the earlier found increase in tonic activity of the diaphragm following lung inflation or deflation during bilateral local vagus cooling to a temperature between 8 and 0-degrees-C is due to afferent impulses in vagal C fibres.

Original languageEnglish
Pages (from-to)280-282
Number of pages3
JournalPflugers archiv-European journal of physiology
Volume421
Issue number2-3
Publication statusPublished - Jun-1992

Keywords

  • VAGAL-A AND VAGAL-C FIBERS
  • LOCAL NERVE COOLING
  • CONDUCTION BLOCK
  • COMPOUND ACTION POTENTIAL
  • RESPIRATORY REFLEXES
  • RABBIT
  • RECEPTORS

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