Effects of transcutaneous electrical nerve stimulation (TENS) on memory in elderly with mild cognitive impairment

MW Luijpen*, DF Swaab, JA Sergeant, KRA van Dijk, EJA Scherder

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)

Abstract

In previous studies, transcutaneous electrical nerve stimulation (TENS) was shown to have a positive effect on memory in Alzheimer's disease (AD) patients. Moreover, the reported effects appeared to be more beneficial in early stages of Alzheimer's disease compared to later stage intervention. Based on this stage-dependency, the present study examined the effects of TENS on memory in a preclinical stage of AD, i.e. in subjects with mild cognitive impairment (MCI). Our results suggest that TENS did not improve memory in a MCI population. Mechanisms that might underlie the absence of positive effects of the TENS treatment in a MCl population are discussed. (C) 2004 Elsevier B.V. All rights reserved.

Original languageEnglish
Pages (from-to)349-357
Number of pages9
JournalBehavioural Brain Research
Volume158
Issue number2
DOIs
Publication statusPublished - 30-Mar-2005
Externally publishedYes

Keywords

  • trancutaneous electrical nerve stimulation (TENS)
  • memory
  • cognition
  • mild cognitive impairment (MCI)
  • aging
  • PROBABLE ALZHEIMERS-DISEASE
  • FREELY MOVING RATS
  • AFFECTIVE BEHAVIOR
  • SPINAL PATHWAYS
  • BASALIS NEURONS
  • LOCUS COERULEUS
  • CHRONIC PAIN
  • DEMENTIA
  • NUCLEI
  • HIPPOCAMPUS

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