Endarterectomy or carotid artery stenting: the quest continues part two

Joe L. Kolkert; Robbert Meerwaldt; Robert H. Geelkerken; Clark J. Zeebregts

doi:10.1016/j.amjsurg.2014.06.012

Endarterectomy or carotid artery stenting: the quest continues part two

Joe L. Kolkert^*, Robbert Meerwaldt, Robert H. Geelkerken, Clark J. Zeebregts

^*Corresponding author for this work

Man, Biomaterials and Microbes (MBM)

Research output: Contribution to journal › Review article › peer-review

8 Citations (Scopus)

Abstract

BACKGROUND: Although randomized trials on carotid artery stenting (CAS) could not establish its equivalence to carotid endarterectomy (CEA) in patients with symptomatic carotid disease, CAS is rapidly evolving. Data on long-term outcome after CAS from randomized trials have now become available and ongoing, prospectively held registries frequently publish their results in increasing numbers of patients. We have therefore reviewed the currently available literature and provide an update of our previous article on this topic.

DATA SOURCES: PubMed literature searches were performed to identify relevant studies regarding current status of CEA and stenting for symptomatic carotid stenosis.

CONCLUSIONS: The efficacy of CAS in patients with symptomatic carotid artery stenosis remains unclear because of varying results in randomized trials. Although multiple registries do report promising results after CAS, peri-interventional stroke/death rates still exceed those rates currently found after CEA. Therefore, CEA remains the "gold standard" in treating these patients. (C) 2015 Elsevier Inc. All rights reserved.

Original language	English
Pages (from-to)	403-412
Number of pages	10
Journal	American Journal of Surgery
Volume	209
Issue number	2
DOIs	https://doi.org/10.1016/j.amjsurg.2014.06.012
Publication status	Published - Feb-2015

Keywords

Carotid artery disease
Stent
Carotid endarterectomy
RANDOMIZED CONTROLLED-TRIAL
TRANSIENT ISCHEMIC ATTACK
STENOSIS EVA-3S TRIAL
FLOW REVERSAL SYSTEM
HIGH-RISK PATIENTS
LEAD-IN PHASE
REVASCULARIZATION ENDARTERECTOMY
CEREBRAL PROTECTION
30-DAY OUTCOMES
PROSPECTIVE REGISTRY

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title = "Endarterectomy or carotid artery stenting: the quest continues part two",

abstract = "BACKGROUND: Although randomized trials on carotid artery stenting (CAS) could not establish its equivalence to carotid endarterectomy (CEA) in patients with symptomatic carotid disease, CAS is rapidly evolving. Data on long-term outcome after CAS from randomized trials have now become available and ongoing, prospectively held registries frequently publish their results in increasing numbers of patients. We have therefore reviewed the currently available literature and provide an update of our previous article on this topic.DATA SOURCES: PubMed literature searches were performed to identify relevant studies regarding current status of CEA and stenting for symptomatic carotid stenosis.CONCLUSIONS: The efficacy of CAS in patients with symptomatic carotid artery stenosis remains unclear because of varying results in randomized trials. Although multiple registries do report promising results after CAS, peri-interventional stroke/death rates still exceed those rates currently found after CEA. Therefore, CEA remains the {"}gold standard{"} in treating these patients. (C) 2015 Elsevier Inc. All rights reserved.",

keywords = "Carotid artery disease, Stent, Carotid endarterectomy, RANDOMIZED CONTROLLED-TRIAL, TRANSIENT ISCHEMIC ATTACK, STENOSIS EVA-3S TRIAL, FLOW REVERSAL SYSTEM, HIGH-RISK PATIENTS, LEAD-IN PHASE, REVASCULARIZATION ENDARTERECTOMY, CEREBRAL PROTECTION, 30-DAY OUTCOMES, PROSPECTIVE REGISTRY",

author = "Kolkert, {Joe L.} and Robbert Meerwaldt and Geelkerken, {Robert H.} and Zeebregts, {Clark J.}",

year = "2015",

month = feb,

doi = "10.1016/j.amjsurg.2014.06.012",

language = "English",

volume = "209",

pages = "403--412",

journal = "American Journal of Surgery",

issn = "0002-9610",

publisher = "EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC",

number = "2",

}

TY - JOUR

T1 - Endarterectomy or carotid artery stenting

T2 - the quest continues part two

AU - Kolkert, Joe L.

AU - Meerwaldt, Robbert

AU - Geelkerken, Robert H.

AU - Zeebregts, Clark J.

PY - 2015/2

Y1 - 2015/2

N2 - BACKGROUND: Although randomized trials on carotid artery stenting (CAS) could not establish its equivalence to carotid endarterectomy (CEA) in patients with symptomatic carotid disease, CAS is rapidly evolving. Data on long-term outcome after CAS from randomized trials have now become available and ongoing, prospectively held registries frequently publish their results in increasing numbers of patients. We have therefore reviewed the currently available literature and provide an update of our previous article on this topic.DATA SOURCES: PubMed literature searches were performed to identify relevant studies regarding current status of CEA and stenting for symptomatic carotid stenosis.CONCLUSIONS: The efficacy of CAS in patients with symptomatic carotid artery stenosis remains unclear because of varying results in randomized trials. Although multiple registries do report promising results after CAS, peri-interventional stroke/death rates still exceed those rates currently found after CEA. Therefore, CEA remains the "gold standard" in treating these patients. (C) 2015 Elsevier Inc. All rights reserved.

AB - BACKGROUND: Although randomized trials on carotid artery stenting (CAS) could not establish its equivalence to carotid endarterectomy (CEA) in patients with symptomatic carotid disease, CAS is rapidly evolving. Data on long-term outcome after CAS from randomized trials have now become available and ongoing, prospectively held registries frequently publish their results in increasing numbers of patients. We have therefore reviewed the currently available literature and provide an update of our previous article on this topic.DATA SOURCES: PubMed literature searches were performed to identify relevant studies regarding current status of CEA and stenting for symptomatic carotid stenosis.CONCLUSIONS: The efficacy of CAS in patients with symptomatic carotid artery stenosis remains unclear because of varying results in randomized trials. Although multiple registries do report promising results after CAS, peri-interventional stroke/death rates still exceed those rates currently found after CEA. Therefore, CEA remains the "gold standard" in treating these patients. (C) 2015 Elsevier Inc. All rights reserved.

KW - Carotid artery disease

KW - Stent

KW - Carotid endarterectomy

KW - RANDOMIZED CONTROLLED-TRIAL

KW - TRANSIENT ISCHEMIC ATTACK

KW - STENOSIS EVA-3S TRIAL

KW - FLOW REVERSAL SYSTEM

KW - HIGH-RISK PATIENTS

KW - LEAD-IN PHASE

KW - REVASCULARIZATION ENDARTERECTOMY

KW - CEREBRAL PROTECTION

KW - 30-DAY OUTCOMES

KW - PROSPECTIVE REGISTRY

U2 - 10.1016/j.amjsurg.2014.06.012

DO - 10.1016/j.amjsurg.2014.06.012

M3 - Review article

SN - 0002-9610

VL - 209

SP - 403

EP - 412

JO - American Journal of Surgery

JF - American Journal of Surgery

IS - 2

ER -

Endarterectomy or carotid artery stenting: the quest continues part two

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Keywords

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