The research described in this thesis aimed to develop novel approaches to engineer lantibiotics, to control either planktonic pathogens or biofilm-infections. To expand the toolbox of engineering lantibiotics, this thesis furthermore aimed at generating a method for obtaining lanthipeptide synthetases with adapted substrate specificity by directed evolution.
|Qualification||Doctor of Philosophy|
|Place of Publication||[Groningen]|
|Publication status||Published - 2020|