Enterohepatic circulation and cholestasis

Folkert Kuipers

Enterohepatic circulation and cholestasis

Research output: Thesis › Thesis fully internal (DIV)

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Abstract

Sulfated glycolithocholic acid, a major metabolite of the secondary bile acid lithocholic acid in newborns, is highly cholestatic when administered to experimental animals. Its taurine conjugated analogue, on the other hand, is less hepatotoxic. This thesis deals with the pathophysiology of the potentially toxic lithocholic acid sulfates and the possibilities of dietary intervention to prevent their toxic effects. ... Zie: Summary

Original language	English
Qualification	Doctor of Philosophy
Supervisors/Advisors	Fernandes, J.V., Supervisor, External person
Publisher	s.n.
Publication status	Published - 1987

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title = "Enterohepatic circulation and cholestasis",

abstract = "Sulfated glycolithocholic acid, a major metabolite of the secondary bile acid lithocholic acid in newborns, is highly cholestatic when administered to experimental animals. Its taurine conjugated analogue, on the other hand, is less hepatotoxic. This thesis deals with the pathophysiology of the potentially toxic lithocholic acid sulfates and the possibilities of dietary intervention to prevent their toxic effects. ... Zie: Summary",

author = "Folkert Kuipers",

note = "date_submitted:2008 Rights: University of Groningen",

year = "1987",

language = "English",

publisher = "s.n.",

}

TY - THES

T1 - Enterohepatic circulation and cholestasis

AU - Kuipers, Folkert

N1 - date_submitted:2008 Rights: University of Groningen

PY - 1987

Y1 - 1987

N2 - Sulfated glycolithocholic acid, a major metabolite of the secondary bile acid lithocholic acid in newborns, is highly cholestatic when administered to experimental animals. Its taurine conjugated analogue, on the other hand, is less hepatotoxic. This thesis deals with the pathophysiology of the potentially toxic lithocholic acid sulfates and the possibilities of dietary intervention to prevent their toxic effects. ... Zie: Summary

AB - Sulfated glycolithocholic acid, a major metabolite of the secondary bile acid lithocholic acid in newborns, is highly cholestatic when administered to experimental animals. Its taurine conjugated analogue, on the other hand, is less hepatotoxic. This thesis deals with the pathophysiology of the potentially toxic lithocholic acid sulfates and the possibilities of dietary intervention to prevent their toxic effects. ... Zie: Summary

M3 - Thesis fully internal (DIV)

PB - s.n.

ER -