Enzymatic Selectivity in Synthetic Methods

Xue Zhong Zhang*, Rui Zhen Hou, Li Xu, Yi Bing Huang, Miguel Ferrero, Susana Fernández, Vicente Gotor, Alan Taylor, Tek Chand Bhalla, Marloes A. Wijdeven, Piotr Kiełbasiński, Floris P.J.T. Rutjes, Takeshi Sugai, Aya Fujino, Hitomi Yamaguchi, Masaya Ikunaka, Maja Majerić Elenkov, Lixia Tang, Bernhard Hauer, Dick B. Janssen

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

1 Citation (Scopus)


This chapter contains sections titled:

Alcalase‐catalysed Syntheses of Hydrophilic Di‐ and Tri‐peptides in Organic Solvents

Selective Alkoxycarbonylation of 1α,25‐Dihydroxyvitamin D3 Diol Precursor with Candida antarctica Lipase B

The Use of Lipase Enzymes for the Synthesis of Polymers and Polymer Intermediates

Bioconversion of 3‐Cyanopyridine into Nicotinic Acid with Gordona terrae NDB1165

Enzyme‐promoted Desymmetrization of Prochiral Dinitriles

Epoxide Hydrolase‐catalyzed Synthesis of (R)‐3‐Benzyloxy‐2‐methylpropane‐1,2‐diol

One‐pot Biocatalytic Synthesis of Methyl (S)‐4‐Chloro‐3‐hydroxybutanoate and Methyl (S)‐4‐Cyano‐3‐hydroxybutanoate

Original languageEnglish
Title of host publicationPractical Methods for Biocatalysis and Biotransformations
EditorsJohn Whittall, Peter Sutton
Number of pages5
ISBN (Electronic)9780470748589
ISBN (Print)9780470519271
Publication statusPublished - 15-Dec-2009


  • Alcalase-catalysed syntheses of hydrophilic di- and tri-peptides in organic solvents
  • Bioconversion of 3-cyanopyridine into nicotinic acid
  • Enzymatic selectivity in synthetic methods
  • Enzyme-catalysed polyurethane solution polymerization using diphenyl ether
  • Enzyme-promoted desymmetrization of prochiral dinitriles
  • High-yielding enzymatic protocol for regioselective alkoxycarbonylation of diol precursor
  • Lipase enzymes in polymer synthesis
  • Novel urethane polyester enzymatic synthesis
  • Oxazolidine ester synthesis
  • Selective alkoxycarbonylation of 1α,25-dihydroxyvitamin D3 diol precursor

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