ERYTHROCYTE AND PLASMA-CHOLESTEROL ESTER LONG-CHAIN POLYUNSATURATED FATTY-ACIDS OF LOW-BIRTH-WEIGHT BABIES FED PRETERM FORMULA WITH AND WITHOUT RIBONUCLEOTIDES - COMPARISON WITH HUMAN-MILK

HA WOLTIL*, CM VANBEUSEKOM, AD SIEMENSMA, HA POLMAN, FAJ MUSKIET, A OKKEN

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

21 Citations (Scopus)

Abstract

We investigated whether a regular formula for premature infants (pre) supplemented with ribonucleotides (pre+RN) raises erythrocyte and plasma cholesterol ester (CE) long-chain polyunsaturated fatty acids (LCPUFAs) of low-birthweight babies (less than or equal to 2.50 kg) compared with their breast-fed counterparts. From days 11 to 42, 31 babies received the pre formula and 37 received pre+RN. Eleven breast-fed babies served as a reference group. Erythrocytes and CE fatty acids were determined on days 11, 21, and 42. There were no differences in the courses of erythrocytes and CE fatty acids between pre formula-fed and pre+RN-fed babies. On day 42, formula-fed babies had lower erythrocytes and CE n-3 and n-6 LCPUFAs compared with breast-fed babies. Subdivision into gestational age- and body weight-matched subgroups gave similar results. RN supplementation does not augment the erythrocyte and CE LCPUFA status of formula-fed babies.

Original languageEnglish
Pages (from-to)943-949
Number of pages7
JournalAmerican Journal of Clinical Nutrition
Volume62
Issue number5
Publication statusPublished - Nov-1995

Keywords

  • RIBONUCLEOTIDE SUPPLEMENTATION
  • INFANT FORMULAS
  • HUMAN MILK
  • LOW-BIRTH-WEIGHT BABIES
  • LONG-CHAIN POLYUNSATURATED FATTY ACIDS
  • ERYTHROCYTES
  • PLASMA CHOLESTEROL ESTERS
  • CAPILLARY GAS-CHROMATOGRAPHY
  • VISUAL-ACUITY DEVELOPMENT
  • DIETARY NUCLEOTIDES
  • SPLIT INJECTION
  • METHYL-ESTERS
  • TERM INFANTS
  • REQUIREMENTS
  • ACCRETION
  • SUPPLEMENTATION
  • MOTHERS

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