Estrogen receptor-alpha-immunoreactive neurons in the periaqueductal gray of the adult ovariectomized female cat

Veronique G.J.M. VanderHorst, Ellie Meijer, Fabienne C. Schasfoort, Fred van Leeuwen, Gert Holstege

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23 Citations (Scopus)

Abstract

Anatomical and physiological studies in rodent and cat have shown that distinct parts of the midbrain periaqueductal gray (FAG) are important for the estrogen dependent, female reproductive behavior. The present study gives a detailed overview of the estrogen receptor-alpha-immunoreactive (ER-IR) neurons in the FAG in the cat. ER-IR neurons were found throughout the rostrocaudal extent of the FAG and laterally adjacent tegmentum, but were most numerous at caudal levels. The lateral and dorsal PAG contained most ER-IR neurons, whereas moderate numbers were found dorsolaterally. In these areas, only very few ER-IR neurons were found near the border of the ependymal layer. Except for the rostral dorsal raphe nucleus, the central PAG contained only few ER-IR neurons. (C) 1998 Elsevier Science Ireland Ltd.

Original languageEnglish
Pages (from-to)13-16
Number of pages4
JournalNeuroscience Letters
Volume240
Issue number1
DOIs
Publication statusPublished - 2-Jan-1998

Keywords

  • midbrain
  • reproductive behavior
  • immunohistochemistry
  • estrogen receptor alpha
  • FINAL COMMON PATHWAY
  • MONOCLONAL-ANTIBODIES
  • CELL GROUPS
  • RAT-BRAIN
  • LOCALIZATION
  • NUCLEUS
  • SYSTEM

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