EVALUATION OF A CYTOLOGICAL SCORING SYSTEM FOR PREDICTING HISTOLOGICAL GRADE AND DISEASE-FREE SURVIVAL IN PRIMARY BREAST-CANCER

H DEGRAAF*, P WILLEMSE, BE LADDE, HA VANDENBERGEN, M KREBBER, T TJABBES, WJ SLUITER

*Corresponding author for this work

    Research output: Contribution to journalArticleAcademicpeer-review

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    Abstract

    A simple cytological scoring system was evaluated as a method of predicting histological grade and disease-free survival in 79 patients with primary breast cancer. The mitotic activity index and oestrogen receptor status were also assessed for their predictive value. The concordance between cytological scores and histological grades was good (80%) for low-grade lesions, but poor (45%) for high-grade lesions. Similar results were found using the mitotic activity index as a prognostic indicator. Cytological grading was not found to be an independent prognostic indicator after a median follow up of 8 years.

    Original languageEnglish
    Pages (from-to)294-300
    Number of pages7
    JournalCytopathology
    Volume5
    Issue number5
    Publication statusPublished - Oct-1994

    Keywords

    • BREAST CANCER
    • CYTOLOGY
    • HISTOLOGICAL GRADE
    • MITOTIC ACTIVITY INDEX
    • ESTROGEN RECEPTOR STATUS
    • PROGNOSIS
    • DISEASE-FREE SURVIVAL
    • ASPIRATION CYTOLOGY
    • NEEDLE ASPIRATION
    • PROGNOSTIC VALUE
    • MORPHOMETRY
    • SPECIMENS
    • CARCINOMAS
    • DIAGNOSIS
    • LESIONS
    • BENIGN

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