F-18-FDG PET for Diagnosing Infections in Prosthetic Joints

Robert M. Kwee; Thomas C. Kwee

doi:10.1016/j.cpet.2019.11.005

F-18-FDG PET for Diagnosing Infections in Prosthetic Joints

Robert M. Kwee, Thomas C. Kwee^*

^*Corresponding author for this work

Basic and Translational Research and Imaging Methodology Development in Groningen (BRIDGE)

Research output: Contribution to journal › Article › Academic › peer-review

22 Citations (Scopus)

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Abstract

Periprosthetic joint infection (PJI) is a severe complication, associated with substantial morbidity and high costs. PJI can occur in the early postoperative period but also many years after joint replacement. Timely and accurate diagnosis is important for treatment planning. Diagnosis of PJI can be a challenge, especially for chronic and low-grade infections. The diagnostic performance of fludeoxyglucose F 18 (¹⁸F-FDG) positron emission tomography (PET) in detecting PJI seems sufficiently high for routine clinical application and has additional value to conventional tests. Further research is needed to determine the exact place of ¹⁸F-FDG PET in the diagnostic work-up of suspected PJI.

Original language	English
Pages (from-to)	197-205
Number of pages	9
Journal	PET Clinics
Volume	15
Issue number	2
DOIs	https://doi.org/10.1016/j.cpet.2019.11.005
Publication status	Published - Apr-2020

Keywords

F-18-FDG PET
Positron emission tomography
Joint
Prosthesis Infection
TOTAL HIP
FDG-PET
ECONOMIC BURDEN
ARTHROPLASTY
REPLACEMENT
ACCURACY
SCINTIGRAPHY

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18F-FDG PET for Diagnosing Infections in Prosthetic Joints _ Elsevier Enhanced ReaderFinal publisher's version, 5.56 MBLicence: CC BY-NC-ND

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title = "F-18-FDG PET for Diagnosing Infections in Prosthetic Joints",

abstract = "Periprosthetic joint infection (PJI) is a severe complication, associated with substantial morbidity and high costs. PJI can occur in the early postoperative period but also many years after joint replacement. Timely and accurate diagnosis is important for treatment planning. Diagnosis of PJI can be a challenge, especially for chronic and low-grade infections. The diagnostic performance of fludeoxyglucose F 18 (18F-FDG) positron emission tomography (PET) in detecting PJI seems sufficiently high for routine clinical application and has additional value to conventional tests. Further research is needed to determine the exact place of 18F-FDG PET in the diagnostic work-up of suspected PJI.",

keywords = "F-18-FDG PET, Positron emission tomography, Joint, Prosthesis Infection, TOTAL HIP, FDG-PET, ECONOMIC BURDEN, ARTHROPLASTY, REPLACEMENT, ACCURACY, SCINTIGRAPHY",

author = "Kwee, {Robert M.} and Kwee, {Thomas C.}",

year = "2020",

month = apr,

doi = "10.1016/j.cpet.2019.11.005",

language = "English",

volume = "15",

pages = "197--205",

journal = "PET Clinics",

issn = "1556-8598",

publisher = "Elsevier",

number = "2",

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TY - JOUR

T1 - F-18-FDG PET for Diagnosing Infections in Prosthetic Joints

AU - Kwee, Robert M.

AU - Kwee, Thomas C.

PY - 2020/4

Y1 - 2020/4

N2 - Periprosthetic joint infection (PJI) is a severe complication, associated with substantial morbidity and high costs. PJI can occur in the early postoperative period but also many years after joint replacement. Timely and accurate diagnosis is important for treatment planning. Diagnosis of PJI can be a challenge, especially for chronic and low-grade infections. The diagnostic performance of fludeoxyglucose F 18 (18F-FDG) positron emission tomography (PET) in detecting PJI seems sufficiently high for routine clinical application and has additional value to conventional tests. Further research is needed to determine the exact place of 18F-FDG PET in the diagnostic work-up of suspected PJI.

AB - Periprosthetic joint infection (PJI) is a severe complication, associated with substantial morbidity and high costs. PJI can occur in the early postoperative period but also many years after joint replacement. Timely and accurate diagnosis is important for treatment planning. Diagnosis of PJI can be a challenge, especially for chronic and low-grade infections. The diagnostic performance of fludeoxyglucose F 18 (18F-FDG) positron emission tomography (PET) in detecting PJI seems sufficiently high for routine clinical application and has additional value to conventional tests. Further research is needed to determine the exact place of 18F-FDG PET in the diagnostic work-up of suspected PJI.

KW - F-18-FDG PET

KW - Positron emission tomography

KW - Joint

KW - Prosthesis Infection

KW - TOTAL HIP

KW - FDG-PET

KW - ECONOMIC BURDEN

KW - ARTHROPLASTY

KW - REPLACEMENT

KW - ACCURACY

KW - SCINTIGRAPHY

U2 - 10.1016/j.cpet.2019.11.005

DO - 10.1016/j.cpet.2019.11.005

M3 - Article

SN - 1556-8598

VL - 15

SP - 197

EP - 205

JO - PET Clinics

JF - PET Clinics

IS - 2

ER -

F-18-FDG PET for Diagnosing Infections in Prosthetic Joints

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