TY - JOUR
T1 - Factors influencing acute postoperative pain after TORS
AU - Toppenberg, Alexandra Gillisa Lara
AU - van den Bosch, Eric Wessel-Jan
AU - Plaat, Robert Eduard
AU - Halmos, Gyorgy Bela
AU - Wolff, André Paul
AU - Schwandt, Leonora Quirine
PY - 2025/10/25
Y1 - 2025/10/25
N2 - BACKGROUND: Transoral robotic surgery (TORS) is performed for both benign as malignant diseases. It has been suggested that patients treated for benign indications may report higher postoperative pain, though supporting evidence is limited.AIMS/OBJECTIVES: To evaluate which factors are associated with acute postoperative pain severity following TORS.MATERIAL AND METHODS: A retrospective observational cohort study was conducted in patients undergoing TORS. Maximum postoperative pain scores (numerical rating scale, NRS 0-10) were recorded for postoperative day (POD) 1,2,3. Clinically well-controlled pain was defined as NRS < 3. Variables including surgical indication (benign or malignant), gender, age, BMI, analgesic use, chronic pain and antidepressant use were analysed. Univariable and multivariable regression analysis were performed for NRS ≥ 3.RESULTS: Of the 119 cases, the mean maximum POD1 pain score was 2.7 (SD 1.89). Univariable analysis showed higher POD1 were associated with benign disease, chronic pain, pain relief, female gender and age. On multivariable regression analysis, only female gender was significantly associated with NRS ≥3.CONCLUSIONS AND SIGNIFICANCE: Female gender was found to be the only independent predictor of higher postoperative pain, other factors, including surgical indication were not.
AB - BACKGROUND: Transoral robotic surgery (TORS) is performed for both benign as malignant diseases. It has been suggested that patients treated for benign indications may report higher postoperative pain, though supporting evidence is limited.AIMS/OBJECTIVES: To evaluate which factors are associated with acute postoperative pain severity following TORS.MATERIAL AND METHODS: A retrospective observational cohort study was conducted in patients undergoing TORS. Maximum postoperative pain scores (numerical rating scale, NRS 0-10) were recorded for postoperative day (POD) 1,2,3. Clinically well-controlled pain was defined as NRS < 3. Variables including surgical indication (benign or malignant), gender, age, BMI, analgesic use, chronic pain and antidepressant use were analysed. Univariable and multivariable regression analysis were performed for NRS ≥ 3.RESULTS: Of the 119 cases, the mean maximum POD1 pain score was 2.7 (SD 1.89). Univariable analysis showed higher POD1 were associated with benign disease, chronic pain, pain relief, female gender and age. On multivariable regression analysis, only female gender was significantly associated with NRS ≥3.CONCLUSIONS AND SIGNIFICANCE: Female gender was found to be the only independent predictor of higher postoperative pain, other factors, including surgical indication were not.
U2 - 10.1080/00016489.2025.2559881
DO - 10.1080/00016489.2025.2559881
M3 - Article
C2 - 41138230
SN - 0001-6489
JO - Acta oto-Laryngologica
JF - Acta oto-Laryngologica
ER -