Factors that influence disease-specific quality of life or health status in patients with COPD: a systematic review and meta-analysis of Pearson correlations

Ioanna Tsiligianni; Janwillem Kocks; Nikolaos Tzanakis; Nikolaos Siafakas; Thys van der Molen

doi:10.4104/pcrj.2011.00029

Factors that influence disease-specific quality of life or health status in patients with COPD: a systematic review and meta-analysis of Pearson correlations

Ioanna Tsiligianni^*, Janwillem Kocks, Nikolaos Tzanakis, Nikolaos Siafakas, Thys van der Molen

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

164 Citations (Scopus)

Abstract

Background: A major goal in the management of chronic obstructive pulmonary disease (COPD) is to ensure that the burden of the disease for patients with COPD is limited and that patients will have the best possible quality of life.

Aims: To explore all the possible factors that could influence disease-specific quality of life and health status in patients with COPD.

Methods: A systematic review of the literature and a meta-analysis were performed to explore the factors that could have a positive or negative effect on quality of life and/or health status in patients with COPD.

Results: Quality of life and health status are determined by certain factors included gender, disease severity indices, lung function parameters, body mass index, smoking, symptoms, co-morbidity, depression, anxiety, and exacerbations. Factors such as dyspnoea, depression, anxiety and exercise tolerance were found to be more correlated with health status than the widely used spirometric values. Forced expiratory volume in one second had a weak to modest Pearson weighted correlation coefficient which ranged from -0.110 to -0.510 depending on the questionnaire used.

Conclusions: The broad range of determining factors suggests that, in order to reach the management goals, health status should be measured in addition to lung function in patients with COPD. (C) 2011 Primary Care Respiratory Society UK. All rights reserved. I Tsiligianni, et al. Prim Care Respir J 2011; 20(3): 257-268 http://dx.doi.org/10.4104/pcrj.2011.00029

Original language	English
Pages (from-to)	257-268
Number of pages	12
Journal	Primary Care Respiratory Journal
Volume	20
Issue number	3
DOIs	https://doi.org/10.4104/pcrj.2011.00029
Publication status	Published - Sept-2011

Keywords

chronic obstructive pulmonary disease
health status
quality of life
factor correlations
questionnaire
systematic review
OBSTRUCTIVE PULMONARY-DISEASE
GEORGES RESPIRATORY QUESTIONNAIRE
GENDER-ASSOCIATED DIFFERENCES
NONSPECIFIC LUNG-DISEASE
SICKNESS IMPACT PROFILE
HOME NEBULIZED THERAPY
AIR-FLOW OBSTRUCTION
BODY-MASS INDEX
PRIMARY-CARE
DEPRESSIVE SYMPTOMS

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@article{24a2d5a744b2436eb932986dd18ba2e5,

title = "Factors that influence disease-specific quality of life or health status in patients with COPD: a systematic review and meta-analysis of Pearson correlations",

abstract = "Background: A major goal in the management of chronic obstructive pulmonary disease (COPD) is to ensure that the burden of the disease for patients with COPD is limited and that patients will have the best possible quality of life.Aims: To explore all the possible factors that could influence disease-specific quality of life and health status in patients with COPD.Methods: A systematic review of the literature and a meta-analysis were performed to explore the factors that could have a positive or negative effect on quality of life and/or health status in patients with COPD.Results: Quality of life and health status are determined by certain factors included gender, disease severity indices, lung function parameters, body mass index, smoking, symptoms, co-morbidity, depression, anxiety, and exacerbations. Factors such as dyspnoea, depression, anxiety and exercise tolerance were found to be more correlated with health status than the widely used spirometric values. Forced expiratory volume in one second had a weak to modest Pearson weighted correlation coefficient which ranged from -0.110 to -0.510 depending on the questionnaire used.Conclusions: The broad range of determining factors suggests that, in order to reach the management goals, health status should be measured in addition to lung function in patients with COPD. (C) 2011 Primary Care Respiratory Society UK. All rights reserved. I Tsiligianni, et al. Prim Care Respir J 2011; 20(3): 257-268 http://dx.doi.org/10.4104/pcrj.2011.00029",

keywords = "chronic obstructive pulmonary disease, health status, quality of life, factor correlations, questionnaire, systematic review, OBSTRUCTIVE PULMONARY-DISEASE, GEORGES RESPIRATORY QUESTIONNAIRE, GENDER-ASSOCIATED DIFFERENCES, NONSPECIFIC LUNG-DISEASE, SICKNESS IMPACT PROFILE, HOME NEBULIZED THERAPY, AIR-FLOW OBSTRUCTION, BODY-MASS INDEX, PRIMARY-CARE, DEPRESSIVE SYMPTOMS",

author = "Ioanna Tsiligianni and Janwillem Kocks and Nikolaos Tzanakis and Nikolaos Siafakas and {van der Molen}, Thys",

year = "2011",

month = sep,

doi = "10.4104/pcrj.2011.00029",

language = "English",

volume = "20",

pages = "257--268",

journal = "Primary Care Respiratory Journal",

issn = "1475-1534",

number = "3",

}

Factors that influence disease-specific quality of life or health status in patients with COPD: a systematic review and meta-analysis of Pearson correlations. / Tsiligianni, Ioanna; Kocks, Janwillem; Tzanakis, Nikolaos et al.
In: Primary Care Respiratory Journal, Vol. 20, No. 3, 09.2011, p. 257-268.

Research output: Contribution to journal › Review article › peer-review

TY - JOUR

T1 - Factors that influence disease-specific quality of life or health status in patients with COPD

T2 - a systematic review and meta-analysis of Pearson correlations

AU - Tsiligianni, Ioanna

AU - Kocks, Janwillem

AU - Tzanakis, Nikolaos

AU - Siafakas, Nikolaos

AU - van der Molen, Thys

PY - 2011/9

Y1 - 2011/9

N2 - Background: A major goal in the management of chronic obstructive pulmonary disease (COPD) is to ensure that the burden of the disease for patients with COPD is limited and that patients will have the best possible quality of life.Aims: To explore all the possible factors that could influence disease-specific quality of life and health status in patients with COPD.Methods: A systematic review of the literature and a meta-analysis were performed to explore the factors that could have a positive or negative effect on quality of life and/or health status in patients with COPD.Results: Quality of life and health status are determined by certain factors included gender, disease severity indices, lung function parameters, body mass index, smoking, symptoms, co-morbidity, depression, anxiety, and exacerbations. Factors such as dyspnoea, depression, anxiety and exercise tolerance were found to be more correlated with health status than the widely used spirometric values. Forced expiratory volume in one second had a weak to modest Pearson weighted correlation coefficient which ranged from -0.110 to -0.510 depending on the questionnaire used.Conclusions: The broad range of determining factors suggests that, in order to reach the management goals, health status should be measured in addition to lung function in patients with COPD. (C) 2011 Primary Care Respiratory Society UK. All rights reserved. I Tsiligianni, et al. Prim Care Respir J 2011; 20(3): 257-268 http://dx.doi.org/10.4104/pcrj.2011.00029

AB - Background: A major goal in the management of chronic obstructive pulmonary disease (COPD) is to ensure that the burden of the disease for patients with COPD is limited and that patients will have the best possible quality of life.Aims: To explore all the possible factors that could influence disease-specific quality of life and health status in patients with COPD.Methods: A systematic review of the literature and a meta-analysis were performed to explore the factors that could have a positive or negative effect on quality of life and/or health status in patients with COPD.Results: Quality of life and health status are determined by certain factors included gender, disease severity indices, lung function parameters, body mass index, smoking, symptoms, co-morbidity, depression, anxiety, and exacerbations. Factors such as dyspnoea, depression, anxiety and exercise tolerance were found to be more correlated with health status than the widely used spirometric values. Forced expiratory volume in one second had a weak to modest Pearson weighted correlation coefficient which ranged from -0.110 to -0.510 depending on the questionnaire used.Conclusions: The broad range of determining factors suggests that, in order to reach the management goals, health status should be measured in addition to lung function in patients with COPD. (C) 2011 Primary Care Respiratory Society UK. All rights reserved. I Tsiligianni, et al. Prim Care Respir J 2011; 20(3): 257-268 http://dx.doi.org/10.4104/pcrj.2011.00029

KW - chronic obstructive pulmonary disease

KW - health status

KW - quality of life

KW - factor correlations

KW - questionnaire

KW - systematic review

KW - OBSTRUCTIVE PULMONARY-DISEASE

KW - GEORGES RESPIRATORY QUESTIONNAIRE

KW - GENDER-ASSOCIATED DIFFERENCES

KW - NONSPECIFIC LUNG-DISEASE

KW - SICKNESS IMPACT PROFILE

KW - HOME NEBULIZED THERAPY

KW - AIR-FLOW OBSTRUCTION

KW - BODY-MASS INDEX

KW - PRIMARY-CARE

KW - DEPRESSIVE SYMPTOMS

U2 - 10.4104/pcrj.2011.00029

DO - 10.4104/pcrj.2011.00029

M3 - Review article

SN - 1475-1534

VL - 20

SP - 257

EP - 268

JO - Primary Care Respiratory Journal

JF - Primary Care Respiratory Journal

IS - 3

ER -