Fermented, ropy, oat-based products reduce cholesterol levels and stimulate the bifidobacteria flora in humans

O Martensson*, M Biorklund, AM Lambo, M Duenas-Chasco, A Irastorza, O Holst, E Norin, G Welling, R Oste, G Onning

*Corresponding author for this work

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    Abstract

    This investigation determined the effects of fermented oat-based products containing both native and microbial beta-glucans on plasma lipids and on fecal total bacterial count and Bifidobacterium ssp. The study was randomized, double blind with 3 parallel groups. Sixty-two free-living volunteers with moderately increased plasma cholesterol levels were recruited. In the final analysis, 56 subjects remained, as 6 subjects had left the study either due to lack of time (n = 2), unwillingness to continue the regimen (n = 2), or for other reasons (n = 2). During the first 3 weeks, all subjects received a fermented dairy-based product (control product, run-in period). On the following 5 weeks, I group continued with the control product, whereas the other 2 groups were given fermented oat-based products (intervention period, 3-3.5 g native beta-glucans per day). One of the oat products (ropy) was cofermented with an exopolysaccharide-producing strain, Pediococcus damnosus 2.6. A significant (P = .022) reduction in total cholesterol by 6% was observed in volunteers who had eaten the fermented, ropy, oat-based product compared with the control group. No other significant changes in plasma lipids were found. A significant increase in total bacterial count (P = .001) and Bifidobacterium ssp (P = .012) was observed in fecal samples from volunteers in the group who had eaten the fermented, ropy, oat-based product. This study shows that a fermented, ropy, oat-based product, containing both native and microbial glucans, can reduce the blood cholesterol level and also stimulate the bifidobacteria flora in the gastrointestinal tract. (c) 2005 Elsevier Inc. All rights reserved.

    Original languageEnglish
    Pages (from-to)429-442
    Number of pages14
    JournalNutrition Research
    Volume25
    Issue number5
    DOIs
    Publication statusPublished - May-2005

    Keywords

    • exopolysaccharides
    • oats
    • nondairy
    • cholesterol
    • Pediococcus damnosus 2.6
    • prebiotic
    • IN-SITU HYBRIDIZATION
    • SERUM-CHOLESTEROL
    • BETA-GLUCAN
    • HUMAN FECES
    • GERM-FREE
    • NONDAIRY
    • PROBES
    • MILK
    • CONSUMPTION
    • CAPACITY

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