FIRRM and FIGNL1: partners in the regulation of homologous recombination

Stavroula Tsaridou; Marcel A T M van Vugt

doi:10.1016/j.tig.2024.02.007

FIRRM and FIGNL1: partners in the regulation of homologous recombination

Stavroula Tsaridou, Marcel A T M van Vugt^*

^*Corresponding author for this work

Research output: Contribution to journal › Short survey › peer-review

3 Citations (Scopus)

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Abstract

DNA repair through homologous recombination (HR) is of vital importance for maintaining genome stability and preventing tumorigenesis. RAD51 is the core component of HR, catalyzing the strand invasion and homology search. Here, we highlight recent findings on FIRRM and FIGNL1 as regulators of the dynamics of RAD51.

Original language	English
Pages (from-to)	467-470
Number of pages	4
Journal	Trends in Genetics
Volume	40
Issue number	6
Early online date	16-Mar-2024
DOIs	https://doi.org/10.1016/j.tig.2024.02.007
Publication status	Published - Jun-2024

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@article{65b337b3c87f4b76a059f4570e68efa2,

title = "FIRRM and FIGNL1: partners in the regulation of homologous recombination",

abstract = "DNA repair through homologous recombination (HR) is of vital importance for maintaining genome stability and preventing tumorigenesis. RAD51 is the core component of HR, catalyzing the strand invasion and homology search. Here, we highlight recent findings on FIRRM and FIGNL1 as regulators of the dynamics of RAD51.",

author = "Stavroula Tsaridou and {van Vugt}, {Marcel A T M}",

year = "2024",

month = jun,

doi = "10.1016/j.tig.2024.02.007",

language = "English",

volume = "40",

pages = "467--470",

journal = "Trends in Genetics",

issn = "0168-9525",

publisher = "ELSEVIER SCIENCE LONDON",

number = "6",

}

TY - JOUR

T1 - FIRRM and FIGNL1

T2 - partners in the regulation of homologous recombination

AU - Tsaridou, Stavroula

AU - van Vugt, Marcel A T M

PY - 2024/6

Y1 - 2024/6

N2 - DNA repair through homologous recombination (HR) is of vital importance for maintaining genome stability and preventing tumorigenesis. RAD51 is the core component of HR, catalyzing the strand invasion and homology search. Here, we highlight recent findings on FIRRM and FIGNL1 as regulators of the dynamics of RAD51.

AB - DNA repair through homologous recombination (HR) is of vital importance for maintaining genome stability and preventing tumorigenesis. RAD51 is the core component of HR, catalyzing the strand invasion and homology search. Here, we highlight recent findings on FIRRM and FIGNL1 as regulators of the dynamics of RAD51.

U2 - 10.1016/j.tig.2024.02.007

DO - 10.1016/j.tig.2024.02.007

M3 - Short survey

C2 - 38494375

SN - 0168-9525

VL - 40

SP - 467

EP - 470

JO - Trends in Genetics

JF - Trends in Genetics

IS - 6

ER -

FIRRM and FIGNL1: partners in the regulation of homologous recombination

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