FIRRM and FIGNL1: partners in the regulation of homologous recombination

Stavroula Tsaridou, Marcel A T M van Vugt*

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

Abstract

DNA repair through homologous recombination (HR) is of vital importance for maintaining genome stability and preventing tumorigenesis. RAD51 is the core component of HR, catalyzing the strand invasion and homology search. Here, we highlight recent findings on FIRRM and FIGNL1 as regulators of the dynamics of RAD51.

Original languageEnglish
JournalTrends in Genetics
DOIs
Publication statusE-pub ahead of print - 16-Mar-2024

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