Fluid resuscitation during persistent postpartum haemorrhage and maternal outcome: A nationwide cohort study

TeMpOH-Study Grp, Dacia D. C. A. Henriquez, Kitty W. M. Bloemenkamp, Rosanne M. Loeff, Joost J. Zwart, Jos J. M. van Roosmalen, Jaap Jan Zwaginga, Johanna G. van der Bom*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

Objective: To determine the association between increasing volumes of crystalloids and colloids administered before transfusion of packed red blood cells in women with persistent postpartum haemorrhage and adverse maternal outcomes.

Study design: Retrospective cohort study in the Netherlands. Women with persistent postpartum haemorrhage and known clear fluids volume for resuscitation were included. Women who received

Results: Of the 883 included women, 199 received 2 to 3 to 4 to 5 to 3 to 4 to 5 to

Conclusion: Clear fluids volume >4 L was independently associated with adverse maternal outcome in women with persistent postpartum haemorrhage. (C) 2019 Elsevier B.V. All rights reserved.

Original languageEnglish
Pages (from-to)49-56
Number of pages8
JournalEUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
Volume235
DOIs
Publication statusPublished - Apr-2019

Keywords

  • Blood transfusion
  • Crystalloid solutions
  • Colloids
  • Postpartum haemorrhage
  • Resuscitation
  • RED-BLOOD-CELLS
  • THROMBIN GENERATION
  • TRAUMA PATIENTS
  • ERYTHROCYTES
  • COAGULOPATHY
  • CRYSTALLOIDS
  • COLLOIDS

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