@article{e1efd384bd9245bf8dd6bd8ea116143c,
title = "Fluorene-Based Multicomponent Reactions",
abstract = "Fluorene and fluorenone are privileged structures with extensive utility in both materials science and drug discovery. Here, we describe syntheses of those moieties through isocyanide-based multicomponent reactions (IMCRs) and the incorporation of the products in diverse and complex derivatives that can be further utilized. We performed six different IMCRs, based on the dual functionality of 9-isocyano-9H-fluorene, and we describe 23 unprecedented adducts.",
keywords = "fluorene, fluorenone, isocyanofluorene, multicomponent reactions, spiro compounds, Ugi reaction",
author = "Xiaofang Lei and Maria Thomaidi and Angeli, {Giasemi K.} and Alexander D{\"o}mling and Neochoritis, {Constantinos G.}",
note = "Funding Information: The research project was supported by the Hellenic Foundation for Research and Innovation (H.F.R.I.) under the {\textquoteleft}2nd Call for H.F.R.I. Research Projects to support Post-Doctoral Researchers{\textquoteright} (Project Number: 0911). X.L. acknowledges support from the China Scholarship Council. This project has received funding (to A.D.) from the European Lead Factory (IMI) under Grant Agreement 115489, the Qatar National Research Foundation (NPRP6-065-3-012), the European Union{\textquoteright}s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie [ITN {\textquoteleft}Accelerated Early stage drug dIScovery{\textquoteright}, Grant Agreement 675555; Cofunds ALERT (665250) and PROMINENT (754425)].H2020MaieSklodowkaCuieAcions754425)QaarNational ReseachFundNPRP6065-3012H2020MaieSklodowkaCuieAcions675555HellenicFoundaionforReearchandInnovaion(0911ChinaScholahipCouncil() Publisher Copyright: {\textcopyright} 2021. Thieme. All rights reserved.",
year = "2022",
month = jan,
day = "1",
doi = "10.1055/a-1471-9080",
language = "English",
volume = "33",
pages = "155--160",
journal = "Synlett",
issn = "0936-5214",
publisher = "GEORG THIEME VERLAG KG",
number = "2",
}