Fragmentation of α- and β-alanine molecules by ions at Bragg-peak energies

S. Bari*, P. Sobocinski, J. Postma, F. Alvarado, R. Hoekstra, V. Bernigaud, B. Manil, J. Rangama, B. Huber, T. Schlathoelter

*Corresponding author for this work

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    Abstract

    The interaction of keV He(+), He(2+), and O(5+) ions with isolated alpha and beta isomers of the amino acid alanine was studied by means of high resolution coincidence time-of-flight mass spectrometry. We observed a strong isomer dependence of characteristic fragmentation channels which manifests in strongly altered branching ratios. Despite the ultrashort initial perturbation by the incoming ion, evidence for molecular rearrangement leading to the formation of H(3)(+) was found. The measured kinetic energies of ionic alanine fragments can be sufficient to induce secondary damage to DNA in a biological environment. (C) 2008 American Institute of Physics.

    Original languageEnglish
    Article number074306
    Number of pages6
    JournalJournal of Chemical Physics
    Volume128
    Issue number7
    DOIs
    Publication statusPublished - 21-Feb-2008

    Keywords

    • GAS-PHASE
    • AMINO-ACIDS
    • IONIZATION
    • ELECTRONS

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