Free Air Intraperitoneally During Chemotherapy for Acute Lymphoblastic Leukemia: Consider Pneumatosis Cystoides Intestinalis

Ellis Groninger; Jan B. F. Hulscher; Bert Timmer; Rienk Y. J. Tamminga; Paul M. A. Broens

doi:10.1097/MPH.0b013e3181ced397

Free Air Intraperitoneally During Chemotherapy for Acute Lymphoblastic Leukemia: Consider Pneumatosis Cystoides Intestinalis

Ellis Groninger^*, Jan B. F. Hulscher, Bert Timmer, Rienk Y. J. Tamminga, Paul M. A. Broens

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

13 Citations (Scopus)

Abstract

Intraperitoneal free air in a child with acute lymphoblastic leukemia (ALL) treated with induction chemotherapy is an ominous sign suspective of gastrointestinal perforation. We report a case of pneumatosis cystoides intestinalis (PCI) with free intraperitoneal air without bowel perforation in a child with Down syndrome during ALL induction treatment. PCI is a physical sign characterized by gas-filled cysts of the submucosa or subserosa of the bowel that can lead to pneumoperitoneum. Clinical management of this case in respect to reported literature on PCI and specific characteristics of patients treated with ALL induction chemotherapy are discussed.

Original language	English
Pages (from-to)	141-143
Number of pages	3
Journal	Journal of pediatric hematology oncology
Volume	32
Issue number	2
DOIs	https://doi.org/10.1097/MPH.0b013e3181ced397
Publication status	Published - Mar-2010

Keywords

pneumatosis (cystoides) intestinalis
(acute lymphoblastic) leukemia
chemotherapy
pneumoperitoneum
child
Down syndrome
CHILDREN
PNEUMOPERITONEUM

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@article{07bfad46846849e39d2cd22afa5f2922,

title = "Free Air Intraperitoneally During Chemotherapy for Acute Lymphoblastic Leukemia: Consider Pneumatosis Cystoides Intestinalis",

abstract = "Intraperitoneal free air in a child with acute lymphoblastic leukemia (ALL) treated with induction chemotherapy is an ominous sign suspective of gastrointestinal perforation. We report a case of pneumatosis cystoides intestinalis (PCI) with free intraperitoneal air without bowel perforation in a child with Down syndrome during ALL induction treatment. PCI is a physical sign characterized by gas-filled cysts of the submucosa or subserosa of the bowel that can lead to pneumoperitoneum. Clinical management of this case in respect to reported literature on PCI and specific characteristics of patients treated with ALL induction chemotherapy are discussed.",

keywords = "pneumatosis (cystoides) intestinalis, (acute lymphoblastic) leukemia, chemotherapy, pneumoperitoneum, child, Down syndrome, CHILDREN, PNEUMOPERITONEUM",

author = "Ellis Groninger and Hulscher, {Jan B. F.} and Bert Timmer and Tamminga, {Rienk Y. J.} and Broens, {Paul M. A.}",

year = "2010",

month = mar,

doi = "10.1097/MPH.0b013e3181ced397",

language = "English",

volume = "32",

pages = "141--143",

journal = "Journal of pediatric hematology oncology",

issn = "1077-4114",

publisher = "LIPPINCOTT WILLIAMS & WILKINS",

number = "2",

}

TY - JOUR

T1 - Free Air Intraperitoneally During Chemotherapy for Acute Lymphoblastic Leukemia

T2 - Consider Pneumatosis Cystoides Intestinalis

AU - Groninger, Ellis

AU - Hulscher, Jan B. F.

AU - Timmer, Bert

AU - Tamminga, Rienk Y. J.

AU - Broens, Paul M. A.

PY - 2010/3

Y1 - 2010/3

N2 - Intraperitoneal free air in a child with acute lymphoblastic leukemia (ALL) treated with induction chemotherapy is an ominous sign suspective of gastrointestinal perforation. We report a case of pneumatosis cystoides intestinalis (PCI) with free intraperitoneal air without bowel perforation in a child with Down syndrome during ALL induction treatment. PCI is a physical sign characterized by gas-filled cysts of the submucosa or subserosa of the bowel that can lead to pneumoperitoneum. Clinical management of this case in respect to reported literature on PCI and specific characteristics of patients treated with ALL induction chemotherapy are discussed.

AB - Intraperitoneal free air in a child with acute lymphoblastic leukemia (ALL) treated with induction chemotherapy is an ominous sign suspective of gastrointestinal perforation. We report a case of pneumatosis cystoides intestinalis (PCI) with free intraperitoneal air without bowel perforation in a child with Down syndrome during ALL induction treatment. PCI is a physical sign characterized by gas-filled cysts of the submucosa or subserosa of the bowel that can lead to pneumoperitoneum. Clinical management of this case in respect to reported literature on PCI and specific characteristics of patients treated with ALL induction chemotherapy are discussed.

KW - pneumatosis (cystoides) intestinalis

KW - (acute lymphoblastic) leukemia

KW - chemotherapy

KW - pneumoperitoneum

KW - child

KW - Down syndrome

KW - CHILDREN

KW - PNEUMOPERITONEUM

U2 - 10.1097/MPH.0b013e3181ced397

DO - 10.1097/MPH.0b013e3181ced397

M3 - Article

SN - 1077-4114

VL - 32

SP - 141

EP - 143

JO - Journal of pediatric hematology oncology

JF - Journal of pediatric hematology oncology

IS - 2

ER -

Free Air Intraperitoneally During Chemotherapy for Acute Lymphoblastic Leukemia: Consider Pneumatosis Cystoides Intestinalis

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