From plugging air leaks to reducing lung volume: a review of the many uses of endobronchial valves

Jorrit B.A. Welling*, T. David Koster, Dirk Jan Slebos

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)
17 Downloads (Pure)

Abstract

Introduction: One-way endobronchial valve treatment improves lung function, exercise capacity, and quality of live in patients with severe emphysema and hyperinflation. Other areas of therapeutic application include treatment of persistent air leak (PAL), giant emphysematous bullae, native lung hyperinflation, hemoptysis, and tuberculosis.

Areas covered: In this review, we will assess the clinical evidence and safety of the different applications of one-way endobronchial valves (EBV).

Expert opinion: There is solid clinical evidence for the use of one-way EBV for lung volume reduction in emphysema. Treatment with one-way EBV can be considered for the treatment of PAL. The application of one-way EBV for giant bullae, post lung transplant native lung hyperinflation, hemoptysis, and tuberculosis is under investigation and more research is required to investigate the efficacy and safety of these applications.

Original languageEnglish
Pages (from-to)721-727
Number of pages7
JournalExpert review of medical devices
Volume20
Issue number9
Early online date7-Jul-2023
DOIs
Publication statusPublished - 2023

Keywords

  • bronchoscopic lung volume reduction
  • Endobronchial valves
  • hemoptysis
  • native lung hyperinflation
  • persistent air leak

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