Glycosylation of Immunoglobulin G Associates With Clinical Features of Inflammatory Bowel Diseases.

The Inflammatory Bowel Disease Biomarkers Consortium, Guinevere S.M. . Kammeijer

Research output: Contribution to journalArticleAcademicpeer-review

86 Citations (Scopus)

Abstract

Causes of inflammatory bowel diseases are not well understood and the most prominent forms, Crohn’s disease (CD) and ulcerative colitis (UC), are sometimes hard to distinguish. Glycosylation of IgG has been associated with CD and UC. IgG Fc-glycosylation affects IgG effector functions. We evaluated changes in IgG Fc-glycosylation associated with UC and CD, as well as with disease characteristics in different patient groups.
Original languageEnglish
Pages (from-to)1320-1333.e10
Number of pages24
JournalGastroenterology
Volume154
Issue number5
DOIs
Publication statusPublished - Jan-2018
Externally publishedYes

Cite this