Wastewater treatment plants (WWTPs) alleviate water pollution but also induce resource consumption and environmental impacts especially greenhouse gas (GHG) emissions. Mitigating GHG emissions of WWTPs can contribute to achieving carbon neutrality in China. But there is still a lack of a high-resolution and time-series GHG emission inventories of WWTPs in China. In this study, we construct a firm-level emission inventory of WWTPs for CH4, N2O and CO2 emissions from different wastewater treatment processes, energy consumption and effluent discharge for the time-period from 2006 to 2019. We aim to develop a transparent, verifiable and comparable WWTP GHG emission inventory to support GHG mitigation of WWTPs in China.